Medicinal & Aromatic Plants
Open Access

Department of Pharmaceutical sciences, Institute of Pharmaceutical sciences, Jinnah Sindh Medical University, 75510, Karachi, Pakistan

Publications

• Research Article   
  Musa paradisiaca L. May Restore Pancreatic Morphology and Function to Trigger its Anti-Diabetic and Hypolipidemic Activities in Alloxon-Induce Diabetic Rats
  Author(s): Khizar A, Rizwania GH, Zahida H, Shareef H and Taqi MM*
  
  Prevalence of diabetes mellitus is on steady rise, though several therapeutic options are available to treat diabetes mellitus. Medicinal plants are in use alongside prescribed therapies; however more research on medicinal plants is warranted to retrieve their anti-diabetic mechanisms to develop low cost, safe and effective anti-diabetic drugs. Aim of current study is to (a) determine antidiabetic and hypolipidemic potential of organic extract of Musa paradisiaca L. (b) to retrieve underlying mechanisms responsible for anti-diabetic effects triggered by the plant. Alloxan was used to induce diabetes mellitus in rates. Two standard drugs (Glibenclamide 2.5 mg/kg, insulin 4 U/200 mg/dl blood glucose) and various doses of organic plant extract from different morphological parts (100 mg/kg, 250 mg/kg and 500 mg/kg) were administered orally to the groups of healthy and diabetic ra.. Read More»
  DOI: 10.35248/2167-0412.19.8.333

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