ISSN: 2167-0870
+44 1478 350008
Department of Cardiology, Aswan University, Egypt
Research Article
Assessment of the Relationship between Galectine-3 and Cardiac Functions in Patients with Chronic Heart Failure
Author(s): Saud Mohamed Elsaughier*, Mohamed Kamal Salama, Amr Hanafy, Mahmoud M Ahmed and Ayman M Ibrahim
Background: HF biomarkers have growing importance in daily clinical practice as well as in clinical trials. Several biomarkers are used for diagnosis and prognosis of HF patients. Recently, Galectine-3 has been proposed for diagnosis and prognosis of HF. In this study we aimed to determine the relationship between galectine-3 level and cardiac functions in patients with chronic heart failure and its correlation with clinical manifestations. Methods: The current study enrolled 90 patients with chronic heart failure and then divided according to ejection fraction (EF) into two groups , group I included 60 patients with clinical manifestation of HF and EF <50%, group II included patients with clinical manifestation of HF and EF >50%.serum levels of Galectine-3 were measured in all patients with heart failure. Results: Level of galectine-3 was significantly increasing with advancing.. View More»
DOI:
10.35248/2167-0870.20.10.408