Translational Medicine

Translational Medicine
Open Access

ISSN: 2161-1025

+44 7460731551

Rossi E

Department of Radiology, Santobono-Pausilipon Children Hospital, Italy

  • Review   
    Current Role of Imaging in the Management of Children with Wilms Tumor According to the New UMBRELLA Protocol
    Author(s): Brillantino C, Rossi E, Minelli R*, Bignardi E, Coppola M, Zeccolini R and Zeccolini M

    Wilms Tumor is the most common primary renal tumor in childhood. Children with Wilms Tumor typically present with an asymptomatic abdominal mass, usually detected on a routine medical checkup or discovered coincidentally by parents. The initial differential diagnosis is with extrarenal abdominal masses; once a tumor of renal origin is established, distinguishing between Wilms Tumor and other primary renal neoplasms such as congenital mesoblastic nephroma, clear cell sarcoma, malignant rhabdoid tumor and renal cell carcinoma may not be easy. However, in many cases imaging findings in conjunction with the patient's clinical and epidemiological data, allow the diagnosis of Wilms Tumor. Wilms Tumor care offers one of the most striking examples of success of pediatric oncology. Over the last decades the European SIOP studies have been the key to developing standardized diagnostic proce.. Read More»

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