Journal of Chromatography & Separation Techniques
Open Access
ISSN: 2157-7064
ISSN: 2157-7064
Department of Pharmaceutical Chemistry, University of King Khalid, Abha, Saudi Arabia
Research Article
Development of HPTLC Method for the Analysis of Flavonoids and Tri-terpenoid Glycoside Isolated from Carya Illinoinensis Bark and their Biological Activity: A Brief Report
Author(s): Md. Sarfaraj Hussain* and Mohd. Zaheen Hassan
Medicinal uses of Carya illinoinensis have drawn the attention of researchers towards identifying and establishing the
active principles responsible for different biological activities. Application of advanced tools and techniques has been
in isolating and studying a new active principle CI-01 from the bark of Carya illinoinensis plant besides developing
validated HPTLC method for its ethanolic extract from bark. The active principle CI-01 after its identification as
Farnesoic acid α-L-glucoside has been investigated for its anti-inflammatory and analgesic activity at a dose of 10 mg/
kg body weight. Besides, in silico studies like molecular docking followed by simulation has enabled to predict the
probable mechanism of it studied biological actions... View More»
DOI:
10.35248/2157-7064.22.S1.003