Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Messina, Italy
Research Article
Role of Tocilizumab and High Flow Nasal Cannula in the Clinical Management of Severe Covid-19
Author(s): Andrea Marino*, Federica Cosentino, Alessio Pampaloni, Daniele Scuderi, Vittoria Moscatt, Manuela Ceccarelli, Maria Gussio, Anna Onorante, Aldo Zagami, Salvatore Torrisi, Silvana Grasso, Benedetto Maurizio Celesia, Francesco Benanti, Vincenzo Boscia, Giovanni Vinci, Licia Larocca, Roberto Bruno, Savino Borraccino, Giuseppe Nunnari and Bruno Cacopardo
Background: Since the late 2019, SARS-CoV2 has spread worldwide, leading WHO to declare a pandemic state. Italy resulted deeply affected by the infection, especially the North. Although there is no proven specific treatment for the infection and for the pulmonary disease, several molecules have been tested always comparing efficacy and collateral effects. Oxygen support plays a key role in the management of this type of patients along with the collaboration with intensive care specialists. This case regards a COVID-19 patient whose clinical parameters deteriorated few days after admission and who had been treated with both Tocilizumab and High Flow Nasal Oxygenation. Case presentation: A 55 yo caucasian female was admitted to ED because of fever and dyspnea. Her chest X-ray showed bilateral ground glass areas and blood examinations revealed elevated inflammatory markers along with lym.. View More»