Journal of Probiotics & Health

Journal of Probiotics & Health
Open Access

ISSN: 2329-8901

+32 25889658

Bart Keijser

Department of Preventive Dentistry, Academic Center for Dentistry Amsterdam, University of Amsterdam, Amsterdam, Netherlands

  • Research   
    The i-screen: A Versatile Preclinical Platform for Gut Microbiota Studies
    Author(s): Frank Schuren*, Valeria Agamennone, Bart Keijser, Edwin Abeln, Jos van der Vossen and Roy Montijn

    The gut microbiota is the complex community of microorganisms that inhabit the human intestine. Gut microbes participate in many aspects of human physiology, including health and disease. Food ingredients, drugs and other environmental factors can affect the gut microbiota, with possible consequences on human health. Progress in microbiome research has significantly stimulated and expanded the interest in technologies to study the potential of different products to modulate the gastro-intestinal ecosystem. In this context we have developed a method, called the i-screen, to evaluate the effects of compounds on the human gut microbiota. The i-screen is an in vitro system that allows the anaerobic cultivation of microorganisms obtained from fecal material, and therefore representative of the highly diverse colonic microbiota. By means of specific analyses, the effects .. Read More»
    DOI: 10.35248/2329-8901.19.7.212

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