Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Department of Ophthalmology, Rama Medical College, Mandhana, Kanpur-209217, India
Research Article
To Study the Effect of Oral Vitamin D Supplementation in Dry Eye Patients in a Tertiary Eye Care Center
Author(s): Anurag Kumar Kashyap, Diksha Sareen, Deepak Mishra, Archana Yadav*, OPS Maurya and SK Singh
Purpose: To establish possible association between serum vitamin D deficiency and dry eye disease and determine beneficiary effect of vitamin D supplementation in dry eye patients.
Materials and methods: A randomized controlled clinical study was conducted in a hospital-based tertiary eye care center including 497 outpatients between age group 18-58 years. Patients were screened randomly for dry eye. Tear film Break-Up Time (TBUT), Schirmer’s test and Ocular Surface Disease Index (OSDI) were used to diagnose dry eye.
Results: Forty patients were diagnosed with dry eye. After vitamin D supplementation in dry eye patients, TBUT and schirmer’s score was found to be significantly higher at 2 weeks (p<0.001) and at 6 weeks of treatment (p<0.001). Also, OSDI score was significantly lowered at 6 weeks of.. View More»