Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Department of Ophthalmology, Science Center Bemcom, Moscow, Russia
Research Article
Thermo and Photoreceptors of Eyes As Regulators of Circadian Rhythm and Glymphatic System
Author(s): Alexander Kholmanskiy*
The dynamics of hydrogen bonds in bulk and hydrated water affected the activation energies of temperature dependence of ion currents of voltage dependent channels that regulate communication and trophic bonds in the neuropil of the cortical parenchyma. The physics of minimizing of isobaric heat capacity of water made it possible to explain stabilization and functional optimization of thermodynamics of eyeball fluids at 34.5°C and human brain during sleep at 36.5°C. At these temperatures, thermoreceptors of cornea and cells of ganglionic layer of the retina, through connections with suprachiasmatic nucleus and pineal gland, switch brain metabolism from daytime to nighttime modes. The phylogenesis of circadian rhythm was reflected in dependence of duration of nighttime sleep of mammals on diameter of eyeball, mass of pineal gland and density of neurons in parenchyma of cortex. T.. View More»
DOI:
10.35248/2155-9570.25.16.1003