Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Yoshiaki Kubo
Institute of Biomedical Sciences, Tokushima University Graduate School,
15-18-3 Kuramoto-cho, Tokushima City, Tokushima 770-8503
Japan
Research Article
Interventional Evaluation of Monoammonium Glycyrrhizinate-Glycine/DLMethionine Combination Tablets in Mild Alopecia Areata
Author(s): Yoshiaki Kubo, Toshitatsu Nogita, Ikuko Kimura, Mami Chiba and Kanako SakakibaraYoshiaki Kubo, Toshitatsu Nogita, Ikuko Kimura, Mami Chiba and Kanako Sakakibara
Objective: Although monoammonium glycyrrhizinate/glycine/DL-methionine (MG) combination tablets have been widely used widely for the treatment of alopecia areata (AA), there are few studies on efficacious combinations with MG. This study was conducted to determine the efficacy and safety of MG plus 5% carpronium chloride (CC).
Methods: In the present interventional study, MG tablets plus 5% carpronium chloride (CC) were compared with CC monotherapy in 31 patients with AA.
Results: There were no significant differences in efficacy between the two groups, and the AA area at 8 and 12 weeks was significantly reduced in both. The results of subanalysis stratified by the presence of allergic factors as determined by IgE level showed that there were also significant decreases in the areas of AA 8 and 12 weeks after the start of.. View More»
DOI:
10.4172/2155-9554.1000322