Journal of Developing Drugs
Open Access

Xuesheng Zheng

Publications

• Research Article
  Dextromethorphan is Effective for Essential Blepharospasm
  Author(s): Xuesheng ZhengXuesheng Zheng
  
  Background: Blepharospasm is a focal dystonia presented with continuous involuntary contractions of the muscles surrounding the eyes, causing frequent eyelid closure and visual disturbance. The current treatments for blepharospasm are not very satisfactory. This is a retrospective study of the therapeutic effect of dextromethorphan on blepharospasm. Methods: This retrospective study included 22 patients with essential blepharospasm, who were treated with dextromethorphan. The effect was evaluated using Jankovic Rating Scale (JRS) and Blepharospasm Disability Index (BSDI). Results: Before dextromethorphan treatment, the baseline JRS score is 5.55 ± 1.10 points, and the BSDI score was 2.87 ± 0.59 points. After 1 week of dextromethorphan treatment, the JRS score decreased to 2.82 ± 0.85 points, an.. View More»
  DOI: 10.4172/2329-6631.1000172

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