Journal of Developing Drugs
Open Access
ISSN: 2329-6631
ISSN: 2329-6631
Tom Friedman
Rambam Health Care Campus,
P.O. Box 9602, Haifa 31096
Israel
Case Report
Acute Respiratory Distress Syndrome Associated with Intravenous Lipid Emulsion Therapy for Verapamil Toxicity, Successfully Treated with Veno-Venous ECMO
Author(s): Tom Friedman, Yair Feld, Zvi Adler, Gil Bolotin and Yedidia BenturTom Friedman, Yair Feld, Zvi Adler, Gil Bolotin and Yedidia Bentur
Calcium channel blocker (CCB) overdose is a potentially fatal poisoning. The use of intravenous lipid emulsion (ILE) therapy for CCB poisoning has emerged in the past few years. In 2017, the American College of Medical Toxicology published interim guidance for the use of ILE resuscitation in these cases. We report an uncommon complication of ILE, acute respiratory distress syndrome, treated with veno-venous extracorporeal membrane oxygenation (ECMO). Case report: A 40-year-old hypertensive woman presented with shock (blood pressure 62/34 mmHg, pulse 86/ min) following ingestion of 4,800 mg verapamil slow release and 1,500 mcg clonidine during a suicide attempt. She was treated with calcium gluconate, sodium bicarbonate, IV high dose insulin, IV glucagon, cardiac amines and vasopressors without response (blood pressure 69/37 mmHg, pulse 78/min). ILE was initiated, and two hours later, .. View More»
DOI:
10.4172/2329-6631.1000182