Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Swarnlata Saraf
University Institute of Pharmacy,
Raipur, Chhattisgarh
India
Short Communication
Comparative Evaluation of Two Different Novel Formulations of Quercetin Against Non Melanoma Skin Cancer in Human Subjects
Author(s): Anshita Gupta, Chanchal Deep Kau and Swarnlata SarafAnshita Gupta, Chanchal Deep Kau and Swarnlata Saraf
Nonmelanoma skin cancer (NMSC) is the steadily increasing cancer in the India. Various studies have put forward strong evidences of NMSC incidence due to UV radiation exposure. Keratinocyte macrophage cells express macrophage which represents both type of receptor viz. folate binding receptor having affinity for folic acid and mannose-binding receptor which are having affinity towards mannose. This study was designed to identify the correlation parameter in evaluation of in vivo doses and epidermal changes following UVB irradiation using noninvasive techniques. We in our study have developed two different formulations embedded with endogenous ligands conjugated nanoparticles of same drug (quercetin) and have analyzed its effect on human volunteers against the release of MIF and MED analysis for which prior permission from Human Ethical Committee has been obtained accordingly. The resu.. View More»
DOI:
10.4172/2155-9554.1000346