Journal of Clinical & Experimental Dermatology Research
Open Access

Sudeep D

Publications

• Case Report
  Klinefelter’s Syndrome with a Cutaneous Manifestation of Lower Limb Ulceration
  Author(s): Jacintha Martis, Ashwini Babu, Sudeep D and John Joseph S Martis Jacintha Martis, Ashwini Babu, Sudeep D and John Joseph S Martis
  
  Klinefelter’s syndrome (KS) is considered the most common type of male hypogonadism. The majority (80-90%) of patients are seen to have 47 XXY karyotype. Leg ulceration has been described as a complication of Klinefelter’s syndrome. A young 21 year old male presented with a non-healing ulcer of the lower extremity of three years duration. Doppler studies and autoimmune workup was negative. However, clinical and further laboratory findings were consistent with Klinefelter’s Syndrome. This case report highlights the importance of screening for chromosomal abnormalities besides evaluating for peripheral vascular disease, venous stasis and diabetes mellitus especially in a young male patient with chronic leg ulceration. .. View More»
  DOI: 10.4172/2155-9554.1000278

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