Rheumatology: Current Research

Rheumatology: Current Research
Open Access

ISSN: 2161-1149 (Printed)

+44-77-2385-9429

Su Zhaz Leon

Su Zhaz Leon

Tanzania

Publications
  • Case Report
    Tacrolimus-Induced Remission in Drug Resistant Inflammatory Myopathy: A Case Series
    Author(s): Karina Rotella, Milena Rodriguez Alvarez, Yair Saperstein, Manjeet S. Bhamra, Su Zhaz Leon, Alekznder Feoktiztov and Isabel MFarlaneKarina Rotella, Milena Rodriguez Alvarez, Yair Saperstein, Manjeet S. Bhamra, Su Zhaz Leon, Alekznder Feoktiztov and Isabel MFarlane

    Idiopathic inflammatory myopathies are rare autoimmune disorders characterized by proximal muscle weakness, elevation of muscle enzymes, abnormal electromyogram and imaging studies revealing areas of edema and inflammation. Initial approach to inflammatory myopathies includes steroids and immunosuppressive agents, with most individuals responding satisfactorily to therapy. However, treatment-refractory myopathies prompts clinicians to use second line agents to achieve remission. In this case series, we describe three patients with refractory idiopathic inflammatory myopathies who were treated with tacrolimus (TAC) added to mycophenolate mofetil (MMF) and steroid therapy, who achieved clinical and biochemical remission... View More»
    DOI: 10.4172/2161-1149.1000238

    Abstract PDF

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