Journal of Osteoporosis and Physical Activity
Open Access

Shinya Hayashi

Publications

• Research Article
  Association of Young Age with Bone Mineral Density Improvement with Denosumab Treatment in Patients with Osteoporosis
  Author(s): Shinya Hayashi, Koji Fukuda, Toshihisa Maeda, Yuji Hiroshima, Nobuaki Chinzei, Shinsuke Kihara, Hanako Nishimoto, Yasushi Miura, Yoshitada Sakai, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Kotaro Nishida and Ryosuke KurodaShinya Hayashi, Koji Fukuda, Toshihisa Maeda, Yuji Hiroshima, Nobuaki Chinzei, Shinsuke Kihara, Hanako Nishimoto, Yasushi Miura, Yoshitada Sakai, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Kotaro Nishida and Ryosuke Kuroda
  
  Introduction: Analysis of predictive factors for the improvement of bone mineral density (BMD) in response to osteoporosis treatment is critical. Several studies reported on the analysis of bone turnover markers as a predictive factor for the improvement of BMD; however, few studies reported on predictive factors other than bone turnover markers. Thus, this study aimed to analyze other predictive factors for distal radial BMD improvement in response to denosumab treatment among patients with osteoporosis.Methods: We evaluated 133 patients with osteoporosis over a 24 month period. All patients received denosumab (60 mg) subcutaneously every 6 months. The BMD of the distal radius was assessed in all patients and serum concentrations of PINP and TRACP5b determined.Results: Denosumab treatment resulted in a 3.3% increase, from.. View More»
  DOI: 10.4172/2329-9509.1000212

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