Clinical Pediatrics: Open Access

Clinical Pediatrics: Open Access
Open Access

ISSN: 2572-0775

+44 1223 790975

Robin M Lloyd

Robin M Lloyd
Mayo Clinic,
200 1st Street SW, Rochester MN

  • Case Report
    DRESS following FIRES: A Clinical Conundrum
    Author(s): Amanda R Dahl, Erin E Knoebel and Robin M LloydAmanda R Dahl, Erin E Knoebel and Robin M Lloyd

    A previously healthy 2-year old Hmong girl presented to the Emergency Department with first time seizures during a febrile illness. Seizures continued for the next two weeks despite multiple antiepileptic agents. All initial cultures and evaluations were negative, and febrile infection related epilepsy syndrome (FIRES) was diagnosed. Three weeks into her hospital course, the patient developed a morbilliform rash on her thigh that became generalized. Concurrently, she developed fever and tachycardia. Laboratory studies demonstrated eosinophilia, an increase in ALT, AST, and direct/total bilirubin. CMV, EBV, and HHV-6 were negative. Skin biopsy showed lichenoid interface dermatitis. Clinical picture was suggestive of drug reaction with eosinophilia and systemic symptoms (DRESS). Topical and systemic steroids were started. Potential triggers for DRESS were discontinued. The patient deter.. View More»
    DOI: 10.4172/2572-0775.1000133

    Abstract PDF

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