Advanced Techniques in Biology & Medicine

Advanced Techniques in Biology & Medicine
Open Access

ISSN: 2379-1764

+44 1223 790975

Rasu Jayabalan

Publications
  • Special Issue Article
    A Protocol to Generate Germ Free Drosophila for Microbial Interaction Studies
    Author(s): Debabrat Sabat, Eldin M Johnson, Arra Abhinay, Rasu Jayabalan and Monalisa MishraDebabrat Sabat, Eldin M Johnson, Arra Abhinay, Rasu Jayabalan and Monalisa Mishra

    Drosophila (fly) gut is used as a model system to study the host microbe interaction. Various developmental, physiological, functional and immunological similarities exist between the gut of the vertebrate and the fly. These similarities advocates their utility as a model system for the study of various gut related diseases. Wild type flies found in its natural environment and those raised in the enclosed laboratory conditions have their own natural microbiota colonizing the gut. This natural gut microbiota may interfere with orally administered microbe-Drosophila interaction studies. To overcome this problem various labs are in the process of raising germ free flies. Germ free Drosophila is completely devoid of intestinal microbiota or any kind of microbial colonization. These germ free fly would be helpful as powerful model in exploring the role of a particular microbial strain or a.. View More»
    DOI: 10.4172/2379-1764.S1-001

    Abstract PDF

Relevant Topics

Top