Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Nevine A. Dorgham
Kasr Al Ainy Hospital,
Egypt
Research Article
Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy
Author(s): Randa M. Youssef, Nevine A. Dorgham, Rehab A. Hegazy, Olfat Shaker and Sara KotbRanda M. Youssef, Nevine A. Dorgham, Rehab A. Hegazy, Olfat Shaker and Sara Kotb
Background: Treatment of Atopic Dermatitis (AD) is still a challenge, with Narrow band (NB-UVB) considered to be a corner stone. Calcidiol deficiency is one of the factors in the pathogenesis of AD, thus supplementation with oral calcidiol is assumed to offer additional therapeutic option for such patients.
Aim of study: Was to assess the possible role of calcidiol in the treatment of AD whether it is induced by phototherapy or given as an oral supplementation.
Patients and methods: 30 pediatric patients with AD were enrolled in this study and divided into 2 equal groups. Group Ι patients received 24 sessions of NB- UVB and group ΙΙ patients received oral calcidiol (600 IU/day orally) for 2 months. A blood sample was taken and SCORAD index was assessed before and after treatment for all patients. 20 contro.. View More»
DOI:
10.4172/2155-9554.1000417