Journal of Osteoporosis and Physical Activity
Open Access
ISSN: 2329-9509
+44 7868 792050
ISSN: 2329-9509
+44 7868 792050
Maria Orbetzova
Bulgaria
Research Article
Bone Mineral Density in Bulgarian Patients with Type 1 Diabetes Mellitus
Author(s): Nikolay Botushanov, Marianna Yaneva, Maria Orbetzova and Albena BotushanovaNikolay Botushanov, Marianna Yaneva, Maria Orbetzova and Albena Botushanova
Aim of the study: To examine the bone mineral density (BMD) in Bulgarian patients with type 1 diabetes mellitus (DM) in comparison to age- sex- and ethnically matched healthy controls and its correlation with bone turnover markers: oteocalcin as a marker of bone formation and deoxypyridinoline cross-laps as bone resorption marker.
Materials and methods: 162 patients with type 1 DM (97 females and 65 males) age 29.17 yrs. (20-40) and 200 (100 women and 100 men) age- and sex matched healthy controls were analyzed for BMD and Z-score of lumbar spine and femoral neck by dual X-ray absorptiometry (DXA) using Lunar DPX-A. Plasma levels of osteocalcin and urine levels of deoxypyridinoline cross-laps were determined.
Results: BMD in type 1 DM showed statistically significant lower levels for lumbar spine L1-L4- men (1.2114 g/ .. View More»
DOI:
10.4172/2329-9509.1000113