Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Lúcia Helena Fávaro Arruda
Head of the Service of Dermatology at the Pontifícia Universidade Católica de Campinas, Campinas (SP), KOLderma Instituto de Pesquisa Clínica Ltda,
Rua Doutor Delfino Cintra, 584-Centro, 13013-055-Campinas-São Paulo
Brazil
Research Article
Evaluation of Clinical Safety and Effectiveness of Hyaluronic Acid-based Temporary Dermal Filler Used in Nasolabial Folds
Author(s): Lúcia Helena Fávaro Arruda, Adilson Costa, Elisangela Samartin Pegas Pereira, Margareth de Oliveira Pereira and Elvira Cancio AssumpçãoLúcia Helena Fávaro Arruda, Adilson Costa, Elisangela Samartin Pegas Pereira, Margareth de Oliveira Pereira and Elvira Cancio Assumpção
Basis: Hyaluronic acid-based temporary dermal filler are used in the treatment of facial folds and wrinkles.
Objectives: Evaluate the effectiveness and safety of Rennova®, a hyaluronic acid-based filler used in nasolabial folds.
Methods: An open label, single-center, phase IV, prospective, observational clinical study, with duration of 360 days, totaling 11 visits. The study included 30 female volunteers, between 30 and 60 years of age, presenting nasolabial folds classified as 3 and 4 according to the Wrinkle Severity Rating Scale and skin phototypes I to V, according to the classification of Fitzpatrick. The effectiveness was subjectively evaluated using the wrinkle severity scale and the Global Aesthetic Improvement Scale and objectively analyzed suing photographs and biopsies. The volunteers gave their opin.. View More»
DOI:
10.4172/2155-9554.1000196