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Journal of Infectious Diseases & Preventive Medicine

Journal of Infectious Diseases & Preventive Medicine
Open Access

ISSN: 2329-8731

Leong KN

Leong KN

Malaysia

Publications
  • Research Article
    Outcome of Isoniazid Preventive Therapy in Adults Living with HIV in Penang, Malaysia
    Author(s): Lim CL, Wong PS, Pereirasamy L, Ang PP, Leong KN and Chow TSLim CL, Wong PS, Pereirasamy L, Ang PP, Leong KN and Chow TS

    Isoniazid preventive therapy (IPT) is a recommended strategy by World Health Organization (WHO) for prevention of active TB infection in people living with HIV. However, data on feasibility and outcome of IPT in Asia are limited. We conducted a retrospective study of 242 HIV patients in Penang who were commenced on IPT between 2011 and 2014, at two HIV specialist clinics in Penang General Hospital and Seberang Jaya Hospital. We evaluated the outcome of IPT in terms of completion rate, adverse events and incidence of active TB. A total of 193 (81.1%) patients completed 6 months of IPT. Patients receiving concurrent highly active antiretroviral therapy (HAART) had significantly higher IPT completion rate (86.1%) compared to those who were not on HAART (67.7%). Major reasons for non-completion were adverse events (21/45) and defaulting from follow-up (17/45). Forty patients (18%) develop.. Read More»
    DOI: 10.4172/2329-8731.1000133

    Abstract PDF

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