Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Kimberly A Tefft
Resurrection Medical Center,
7435 West Talcott Ave, Office of Medical Education, Chicago, IL 60622
Tanzania
Research Article
Is Warfarin Usage A Risk Factor for Cutaneous Calciphylaxis? A Retrospective Analysis
Author(s): Kimberly A Tefft, Jonathan Andrews, Jason B Lee and Rakesh GulatiKimberly A Tefft, Jonathan Andrews, Jason B Lee and Rakesh Gulati
Currently the pathogenesis of cutaneous calciphylaxis, also known as calcemic uremic arteriolopathy, is poorly understood. We sought to evaluate potential risk factors for cutaneous calciphylaxis (CC), specifically warfarin usage prior to CC diagnosis, other anticoagulant usage prior to CC diagnosis, an elevated serum calcium level, an elevated serum phosphate level, a serum calcium and phosphate product greater than 50, hyperparathyroidism, and a history of chronic (stage III-V) kidney disease. We performed a retrospective analysis of all histopathologically confirmed cases of cutaneous calciphylaxis diagnosed at Thomas Jefferson University Hospital between January 1st 1990 and March 1st 2010. Of the thirteen study patients, five (38%) patients had a history of warfarin use, 12 (93%) of patients had elevated intact parathyroid hormone levels, and 12 (93%) of patients suffered from ch.. View More»
DOI:
10.4172/2155-9554.1000114