Clinical Pediatrics: Open Access
Open Access

Hui-Ma

Publications

• Case Report
  X-linked Agammaglobulinemia - Is it Really Rare?
  Author(s): Asfia Banu Pasha, Ya-Yuan Zhang, Hui-Ma, Hai – Guo Yu, Xiao-Qing Chen and Guo-Ping ZhouAsfia Banu Pasha, Ya-Yuan Zhang, Hui-Ma, Hai – Guo Yu, Xiao-Qing Chen and Guo-Ping Zhou
  
  Background: X-Linked Agammaglobulinemia is a disease of the immune system in which there is defective development of the B lymphocytes due to which the production of gammaglobulins is markedly reduced; which results in immunodeficiency and high vulnerability to contract fatal infections. This is the reason for which a patient with XLA presents with history of recurrent infections. XLA is known to be caused due to a mutation in the Btk gene. Btk gene mutation observed on gene mapping markedly reduced levels of B lymphocytes and immunoglobulins; are the confirmatory laboratory findings for the diagnosis of XLA. As there is immunodeficiency in the patient, this condition is treated with intravenous immunoglobulin therapy. In this article, two cases with XLA have been described. Over a period of one month, two cases of XLA were admitted at the hospital. This is to pay att.. View More»
  DOI: 10.4172/2572-0775.1000130

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