Journal of Molecular Imaging & Dynamics
Open Access
ISSN: 2155-9937
ISSN: 2155-9937
Hajra Ashraf
Sialkot Sub Campus, Sialkot, Punjab
Pakistan
Review Article
Fibrinolytic Enzyme: Restoration Tool for Obliteration of Blood Clots
Author(s): Hajra Ashraf, Bisma Meer, Romasa Naz, Aarooj Saeed and Pervez AnwarHajra Ashraf, Bisma Meer, Romasa Naz, Aarooj Saeed and Pervez Anwar
Body interrelated complex system maintain body hemostasis but severe vascular injury reprehensible for thrombus formation. Fibrinogen is a prime protein in fibrinolysis. Complex cascade pathway involves in conversion of plasminogen to plasmin to perform fibrinolysis and plasminogen activating inhibitor (PAI) cease this pathway. The genetic and acquired factors influence clot formation while it curbs by factor VIII. This review aims to illustrate significance of fibrinolytic enzymes, Nattokinase, Urokinase, Staphylokinase and streptokinase as therapeutic agent to control myocardial infraction, venous stroke and pulmonary clotting.
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DOI:
10.4172/2155-9937.1000138