Journal of Developing Drugs
Open Access
ISSN: 2329-6631
ISSN: 2329-6631
Garg R
India
Research Article
Review on Mucoadhesive Drug Delivery System with Special Emphasis on Buccal Route: An Important Tool in Designing of Novel Controlled Drug Delivery System for the Effective Delivery of Pharmaceuticals
Author(s): Singh R, Sharma D and Garg R
Singh R, Sharma D and Garg R
Since, the last four decades, the concept of mucoadhesion has achieved a much valuable interest in the various fields of pharmaceutics. There are many advantages of mucoadhesive buccal drug delivery system that made this a novel drug delivery system for the local as well as systemic delivery of various drugs. The main advantage of this drug delivery system is that it prolongs the residence time of the dosage form at the site of application. Due to the high blood supply and relatively high permeability of the buccal mucosa, the buccal cavity is the best option for both local as well as systemic delivery of various drugs. The term bioadhesion can be defined as a phenomenon of interfacial molecular attractive forces in the midst layer of surface of a biological membrane and the natural or synthetic polymers, which allows the polymer to adhere the surface of that membrane for an extended .. View More»
DOI:
10.4172/2329-6631.1000169