Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Fu-Tang Pan
Shandong Provincial Institute of Dermatology and Venereology,
Jinan, Shandong250022
China
Research Article
Challenging Approach with Nanoformulation and Photodynamic Therapy in Dermatology
Author(s): Fu-Tang Pan, Wei-Zhi Wu, Qiao-Gui Zhi and Qi-Xing LiangFu-Tang Pan, Wei-Zhi Wu, Qiao-Gui Zhi and Qi-Xing Liang
Background:Photodynamic therapy (PDT) and holds substantial promise in improving outcomes of patients with a form of cutaneous conditions and dermatological conditions such as keratosis and basal cell carcinoma, etc. Use of 5-aminolevulinic acid (ALA) was sanctioned as secure and effective for use as a treatment.
Methods:In our work, we used Photodynamic therapy in patients with selected skin cancerization, and evaluated the fluorescence from photo sensitizer to constitute the field cancerization, which helps in analyzing the efficacy of the technique.
Results:From our study, it is clear that use of ALA with PDT against different skin cancerization has significant effects. However, the effect of efficacy varied according to the type of carcinoma. In our study, we observed that nano- ALA with PDT targeted about 70-80% m.. View More»
DOI:
10.4172/2155-9554.1000221