Journal of Alcoholism & Drug Dependence

Journal of Alcoholism & Drug Dependence
Open Access

ISSN: 2329-6488

+44 1223 790975

Craig Hutton

Craig Hutton


  • Review Article
    Assessing Anxiety and Reward-Related Behaviors Following Alcohol Administration or Chronic Stress
    Author(s): Harinder Aujla, Craig Hutton and Benjamin RogalaHarinder Aujla, Craig Hutton and Benjamin Rogala

    Dysregulation of stress- and reward-related neurocircuitry that results from experience with alcohol or chronic stress may underlie vulnerability to initiate or relapse to alcohol use. Related changes in behaviors associated with such dysregulation may provide insight into factors that increase or decrease vulnerability to alcohol dependence in humans. In the present study, anxiety-like behavior and the acquisition of conditioned place preference were assessed in male Wistar rats with differing histories of exposure to stress or alcohol two weeks following the termination of treatment. Thus, time spent on the open arms of the elevated plus maze as well as the number of days required to acquire alcohol-based place conditioning were evaluated in control animals vs. those with a history of exposure to chronic unpredictable stress, experimenter-administered intragastric alcohol, or selfad.. View More»
    DOI: 10.4172/2329-6488.1000136

    Abstract PDF

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