Rheumatology: Current Research
Open Access

Azombakin J

Publications

• Research Article
  Genetic Susceptibility to Rheumatoid Arthritis in West African Patients: Correlation with Rheumatoid Factor, Anticitrullinated Protein Antibody and Radiological Damage
  Author(s): Zomalheto Z*, Assogba M, Avohou G, Azombakin J and Laleye A Zomalheto Z*, Assogba M, Avohou G, Azombakin J and Laleye A
  
  Background: Rheumatoïd arthritis (RA) is characterized by a multifactorial aetiology and a complex genetic background, with the major histocompatibility complex (MHC) region playing a major role. Aim of the work: To detect the genetic susceptibility to RA in Benin population. Patients and Methods: A prospective case-control study was conducted from December 2015 to December 2016. The selected unrelated patients suffered from RA according to the American College of Rheumatology (ACR) criteria. We genotyped HLA-DRB1*01, HLADRB1*04 and HLA-B locus between 52 west african patients with RA and 48 unrelated controls to study the susceptibility of the genes to RA among Patients. Low-resolution genotyping for HLA B and HLADRB1 alleles was performed using Polymerase Chain Reaction and Sequence-Specific Primers (PCR-SSP.. View More»
  DOI: 10.4172/2329-8731.1000221

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