Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Ashish Arshanapalli
Department of Dermatology,
1605 N Delaware St Indianapolis, IN 46202
Tanzania
Case Report
Topical Keratolytics for a Case of Porokeratotic Eccrine Ostial and Dermal Duct Nevus
Author(s): Ashish Arshanapalli, Navid Ezra, Mouhammad Aouthmany, Stefanie Hirano-Ali, Jeffrey B Travers and Nico MousdicasAshish Arshanapalli, Navid Ezra, Mouhammad Aouthmany, Stefanie Hirano-Ali, Jeffrey B Travers and Nico Mousdicas
Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) is a rare disorder of keratinization characterized by the presence of cornoid lamellae and association with eccrine sweat ducts. These lesions are usually benign and asymptomatic, so treatment is often for cosmetic purposes. Current therapies for PEODDN are either insufficient or impractical. We present a case of PEODDN treated with topical tretinoin 0.05% cream and 5-fluorouracil 5% cream with the hopes of providing an efficacious, financially relevant, and well-tolerated treatment regime for PEODDN. The combination of topical tretinoin and 5-fluorouracil did not provide substantial improvement in the lesions of a patient treated with this therapy for 6 weeks, and further studies are needed to identify an efficacious treatment for PEODDN that is both well-tolerated and economically feasible for patients with this condition... View More»
DOI:
10.4172/2155-9554.1000328