Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

Aliaa Atef

Aliaa Atef

Tanta, 31111

  • Research Article
    Expression of Estrogen Receptor Beta in Striae Distensae of Different Sites of the Body
    Author(s): Aliaa Atef and Rania MoustafaAliaa Atef and Rania Moustafa

    Background: Striae distensae (Stretch marks) are common cutaneous lesions that are characterised terminally by linear bands of atrophic skin. They run perpendicular to the direction of skin tension. The pathogenesis of striae remains unclear. The etiological mechanisms involved in striae are usually classified under the headings of genetic predisposition and the mechanical rupture of dermal components as an important initiating event. The estrogen and its receptors can play an important role in the pathogenesis of stretch marks despite their presence in the epidermis. Patients and Methods: This study was carried out on 44 female patients complaining of stretch marks on different body parts. Punch skin biopsies were taken from striae distensae of the abdomen, thighs, breasts and buttocks. Immunohistochemical staining of these samples was done u.. View More»
    DOI: 10.4172/2155-9554.10000312

    Abstract PDF

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