Journal of Alcoholism & Drug Dependence
Open Access

Ali Mahmood Khan

Publications

• Review Article
  Safety and Efficacy of Antipsychotics in Pregnancy and Lactation
  Author(s): Yassar I Odhejo, Afshan Jafri, Hema Madhuri Mekala, Mudasar Hassan, Ali Mahmood Khan, Sabrina K Dar, Rizwan Ahmed Yassar I Odhejo, Afshan Jafri, Hema Madhuri Mekala, Mudasar Hassan, Ali Mahmood Khan, Sabrina K Dar, Rizwan Ahmed
  
  The clinical profiles of antipsychotic medications have improved dramatically since the first generation was introduced in the 1950s. Second Generation Antipsychotic medications (SGAs), which became available in 1990, generate fewer side effects, including reduced incidence of extrapyramidal symptoms such as hyperprolactinemia. This improves the female patients’ ability to become pregnant, a process which is compromised by first generation drugs. However, use of antipsychotic medications has become increasingly prevalent. The likelihood of females with depression, bipolar disorder, psychosis to have an unplanned pregnancy, and the incidence of foetal exposure to psychotropic drugs during the first trimester of pregnancy has also increased. The paucity of exposure and outcome data leaves the safety and effects of use of antipsychotic medications during pregnancy as a subject to c.. View More»
  DOI: 10.4172/2329-6488.1000267

  Abstract PDF

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