Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Adele Sparavigna
DermIng srl, Clinical Research and Bioengineering Institute,
Milan
Italy
Research Article
Anti-Age Activity and Tolerance Evaluation of Collagen Micro-Injection Treatment Associated to Topical Application of a Cosmetic Formulation (Investigator-Initiated Multicentre Trial)
Author(s): Adele Sparavigna, Antonello Tateo, Elena Inselvini, Massimiliano Tocchio, Maria Cristina Orlandini and Giorgio BotaliAdele Sparavigna, Antonello Tateo, Elena Inselvini, Massimiliano Tocchio, Maria Cristina Orlandini and Giorgio Botali
Objective: A novel equine type I collagen treatment consisting of an intradermal injection associated with the use of a topical mousse was developed with characteristics especially suited for global face rejuvenation. A multicenter, investigator-initiated, open clinical trial, conducted by 6 italian centers, was carried out to evaluate the anti-age performance of this combined treatment.
Methods: The study was conducted on 72 female healthy subjects, age range 40-65 years, asking for midface volume restoration and presenting cutaneous aging/photoaging signs. The 1st injection treatment with the injectable product was performed immediately after the basal evaluation (T0). Two touch-up treatments were performed after 2 (T1) and 4 weeks (T2). Collagen mousse was to be applied by the volunteers on the face (including the submental area) twice.. View More»
DOI:
10.4172/2155-9554.1000391