Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Abel Maksoud R
Venereology and Andrology, Faculty of medicine,
10, Mahmoud Sidky street, Louran, Alexandria
Egypt
Case Report
Evaluation of the Efficacy of Injection Lipolysis using Phosphatidylcholine/Deoxycholate Versus Deoxycholate Alone in Treatment of Localized Fat Deposits
Author(s): El Kamshoushy A, Abel Maksoud R and El Mahdy NEl Kamshoushy A, Abel Maksoud R and El Mahdy N
The practice of injection lipolysis, using drugs generally based on phosphatidylcholine and deoxycholate (PCDC), evolved from the initial intravenous use of those drug formulations to treat blood disorders. Formulations containing phosphatidylcholine and bile salts (phosphatidylcholine bile salt formulations, PBF) are increasingly being utilized to treat localized fat accumulation. Several open label clinical studies have reported promising results using injections of PBFs for the treatment of localized fat accumulation, including lower eyelid fat herniation and “buffalo hump” lipodystrophy. Bile salts have been used to improve the aqueous solubility of phosphatidylcholine. Highly purified phosphatidylcholine can be combined with the secondary bile salt sodium deoxycholate, an anti-microbial, benzyl alcohol, and water to form a stable, mixed micelle preparation that .. View More»
DOI:
10.4172/2155-9554.1000146