Transition metal complexes/organometallic compounds as anticancer | 61111
Journal of Thermodynamics & Catalysis

Journal of Thermodynamics & Catalysis
Open Access

ISSN: 2157-7544

Transition metal complexes/organometallic compounds as anticancer/anti HIV Drugs or in pharmaceutical industry

World Summit on Organic and Inorganic Chemistry - September 12, 2022 | Webinar

September 12, 2022 | Webinar

Prakash Kinthada

National Institute Of Medical Sciences(Nimes)University, India.

Scientific Tracks Abstracts: J Thermodyn Catal

Abstract :

Cancer is a dreadful disease and any practical solution in combating this disease is of paramount importance to public health. Cancer patients have burdened by drug induced toxic side effects, and no turned to seek help from the complementary and alternative medicine hoping for a better cure. Research on Platinum based drugs and Non Platinum based drugs is a Multi-Million Dollar Industry in USA and there is every need to produce safe drugs for the cure of this monstrous disease. Flavonoids have a long history of use in traditional medicines in many cultures. The phytochemical, curcumin is one of the major dietary flavonoid, belonging to a group of flavonol, Curcumin is a natural polyphenol. It is highly potential molecule capable of preventing and treating various cancers. Various dietary chemo preventive agents, turmeric powder or its extract are broadly used as therapeutic preparations in Indian System of medicine. We provide a summarized synthesis and structural determination of Curcumin Oxime, Curcumin Thio semi carbazone derivative of Gold (III) complex. The use of these analogs for prevention of cancer tumor progression and treatments of human malignancies. A pharmacologic agent for treating and/or preventing cancer, among other diseases and conditions, and particularly breast, prostate, and pancreatic cancer, in humans and animals. The novel pharmacologic agent is an isoflavonoid or isoflavonoid mimetic covalently attached to a cytotoxic pharmacophore that, preferably has the ability to conjugate with a metal salt to form a more potent metal complex, particularly a Au (III) complex and other complexes of Platinum, Palladium, Ruthenium, Copper etc.

Biography :

Prakash Kinthada is a Professor and Head in Chemistry at National Institute of Medical Sciences (Nims) University, Jaipur, and Rajasthan, India. His Research interests are in the fields of Transition Metal Complexes/Organometallic compounds present in drugs. He attended more over 100 conferences in the fields of Chemistry.