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The reductive mechanisms of the inactivation of NO | 579
Translational Medicine

Translational Medicine
Open Access

ISSN: 2161-1025

+44 1223 790975

The reductive mechanisms of the inactivation of NO


International Conference on Translational Medicine

September 17-19, 2012 Holiday Inn San Antonio, Texas, USA

Tao Li

AcceptedAbstracts: Transl Med

Abstract :

Reductive mechanisms, may also play a role in the inactivation of NO, but such reductive mechanisms are not well characterized. The nitrite sodium was used in an error as sugar to add the noodles in a little store on April 10, 2012, China. About ten men, who ate less fruits and vegetables then ate the noodles, were poisoning, but the other men, who ate more fruits and vegetables then ate the noodles, were safe. Vitamin C plays an important role. If the products, which nitrite reacted with vitamin C, were nitric oxide and carcinogenic N-nitroso compounds, the other men were not safe. We study the chemicals which nitrite reacted to L-ascorbic acid with an elevated L-ascorbic acid to nitrite ratio in the solution. The products, when the nitrite reacted with L-ascorbic in the solution, were nitric oxide (NO), dinitrogen monoxide (N 2 O) and nitrogen gas (N 2 ). The reaction at 25 � , 2H+ + 2NO 2 - + 3C 6 H 8 O 6 N 2 + 4H 2 O + 3C 6 H 6 O 6 , which the value of ∆ G 0 (-806 kJ?mol-1) is large negative and a value of K 0 (1.81�10 141 ) is >>1, corresponds to a thermodynamically favourable reaction and virtually goes to completion. We summarize the related research and think that the nitrogen gas (N 2 ) was one major product which the nitrite reacted with L-ascorbic in the solution. It is true according to chemical thermodynamics and chemical dynamics. It maybe useful to understand the reductive mechanisms of the inactivation of NO and the global recycle of nitrogen.

Biography :

Tao Li has completed his Ph.D at the age of 32 years from Zhongshan University and postdoctoral studies from Huazhong University of Science and Technology, China. He has published more than 10 papers in reputed journals.

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