Virology & Mycology
Open Access
ISSN: 2161-0517
+44 1223 790975
ISSN: 2161-0517
+44 1223 790975
Li Xie, Qinglin Cheng, Hua Ding, Zhou Sun, Xuhui Yang, Qingjun Kao, Renjie Huang and Jing Wang
Posters-Accepted Abstracts: Virol-mycol
Fatalities associated with human infection with H7N9 virus were of great public health concern, and a serious disease that threatens human�??s health. The possible risk factors for death are not, however, fully known yet. The clinical and epidemiological data of 61 H7N9 patients whose diagnoses were confirmed by laboratory tests between 1st March, 2013 and 2nd March, 2014 in Hangzhou were collected. Descriptive analysis and univariate analysis were used to analyze the demographic, clinical and epidemiological characteristics and treatment outcomes. Patients were classified into improvement group and death group according to treatment outcomes, and risk factors for death were explored. Chisquare test and t test were used for statistical analysis. A total of 61 patients were included in this study, among which 20(32.8%) patients died. The ratio of men to women for death attributed to H7N9 infection was three to one. The mean age of patients in death group was (63.6±3.8) years, which was older than that in improvement patients([55.4±2.2] years, t=1.97,P=0.05). The univariate analysis showed that the risk factors of mortality included over 60 years [�?2=5.16,P=0.02,OR= 3.65 (95%CI:1.19 -11.13)], low education level [�?2=5.42,P=0.02, OR=4.20 (95%CI:1.24-14.00)], chronic diseases [�?2=4.67, P=0.03, OR= 3.81 (95% CI:1.12-12.69)],bad hand hygiene[�?2=4.05, P=0.04, OR= 4.67 (95%CI:1.04-11.56)], C-reactive protein(CRP)�?�120mg/L[�?2=4.04, P=0.04,OR=6.00 (95%CI:1.04- 35.33)],increased initial neutrophil count [�?2= 3.90, P=0.05,OR=4.58(95% CI: 1.01�?? 34.22)], and decreased initial lymphocyte count [�?2= 7.12, P=0.01,OR=7.53(95% CI:1.63-24.51)]. Over 60 years, low education 1eve1, chronic diseases, had hand hygiene, CRP�?�120mg/L, and increased initial neutrophil count and decreased initial lymphocyte count are identified as risk factors for death in human avian influenza A(H7N9) cases in Hangzhou.