Predictors of loss to follow up of patients enrolled on anti-retroviral therapy: A retrospective cohort study
Virology & Mycology

Virology & Mycology
Open Access

ISSN: 2161-0517

Predictors of loss to follow up of patients enrolled on anti-retroviral therapy: A retrospective cohort study

International Conference on Retroviruses & Novel Drugs

June 08-09, 2015 Chicago, USA

Kidane Tadesse and Fisaha Haile

Posters-Accepted Abstracts: Virol-mycol

Abstract :

Introduction: There is a growing concern about the increasing rates of Loss to Follow up (LTFU) among people who are on HIV/AIDS treatment programs. It is more common in resource poor settings. However little is known about the time to LTFU and predictors after Anti-retroviral Therapy (ART) initiation in low resource settings including Ethiopia. Method: Retrospective cohort study was employed among a total of 520 records of patients who were enrolled on antiretroviral therapy in Aksum St. Marry hospital. Baseline patient records were extracted from electronic and paper based medical records database and analyzed using Kaplan Meier survival and Cox proportional hazard model to identify the independent predictors of loss to follow up of patients on ART. Result: Among 520 patients, 51(9.8%) were loss giving a LTFU rate of 8.2 per 100 person- years. From these LTFU, 21(41%) occurred within the first six months of ART initiation. The independent predictors of LTFU of patient were being smear positive pulmonary TB [Adj.HR (95% CI)=(2.05 (1.02, 4.12)], male gender [Adj. HR (95%CI)=(2.73 (1.31, 5.66)], regiment AZT-3TC-NVP [Adj. HR (95% CI)=(3.47 (1.02,11.83)] and weight ≥60kg [Adj. HR (95% CI)=(3.47 (1.02,11.83)]. Conclusion: Substantial magnitude of loss to follow up has been found among patients on ART which significantly affect the overall outcome of HIV/AIDS program of treatment. The independent predictors identified were TB smear positive, male gender, regiment AZT-3TC-NVP and lower weight. So, continuous and comprehensive follow up is necessary to minimize loss to follow up and optimize treatment outcome of people on ART.

Biography :

Kidane Tadesse has completed his MSc from Mekelle University College of Health Sciences. He is member of different college committees related to quality of education. He is a Postgraduate program coordinator. He has published more than 10 papers in reputed journals.