Journal of Clinical and Experimental Ophthalmology
Open Access

Post-selective laser trabeculoplasty management should anti-inflammatory be used

Joint Event on 18^th International Conference on Glaucoma & Retinal Diseases & 18^th World Conference on Optometry and Photo Refractive Keratectomy

September 24-25, 2018 | Dallas, USA

Leyla Ali Aljasim

King Khaled Eye Specialist Hospital, Saudi Arabia

Scientific Tracks Abstracts: J Clin Exp Opthamol

Abstract :

Introduction: The use of anti-inflammatory following SLT is controversial; the proposed effect of SLT is biological through the immediate release of Interleukin receptor antagonist within the first 8 hours. Corticosteroids use inhibit Interleukin production, and might compromise SLT effect. In a retrospective review of 215 eyes underwent SLT in our institute; Post-SLT Prednisolone was used in 134eyes, Fluorometholone in 41eyes & 40eyes had neither. In group1 IOP reduction post-SLT was 2.69±5.3mmHg (8.5%), in group2 was 3.4±4.7mmHg (12.9%), in group3 was 5.6±6.2mmHg (21.2%), and there was no difference in the rate of complication between the groups. Method: Patients underwent bilateral SLT, post-SLT one eye was selected randomly to use topical prednisolone for 1 week. Inflammation, discomfort and IOP levels were compared between both eyes for 6months. Result: 16 patients with open-angle glaucomas, age 53.5±12.3 years were enrolled. Group1; used Prednisolone post-SLT, group2 used lubrication only. Baseline IOP in group1 was 24.13±2.4 (21-29) mmHg, and in group2 was 24.56±3.2 (21-32) mmHg. All had bilateral 360° SLT on the same day; 91±10 shots used for group1, and 91±10 shots for Group2 (P=0.81), same energy setting used per patient, with a mean of 0.59±0.13 (0.2-0.7) mj/shot. 6months post-SLT group1 IOP was 17±2 with reduction of 7.2mmHg from baseline IOP, in group2 IOP was 17.7±3 with reduction of 6.8 mmHg (P=0.32) (P=0.60). Conjunctival congestion was more severe & frequent in group2 in day1 (P=0.00) and reduced after 1 week. (P=0.23). Discomfort levels were more severe & frequent in group 2 after 1hour, 1days and 1week, (P=0.43) (P=0.00) (P=1). Conclusion: The use of potent steroid following SLT doesn't have an effect on the final IOP reduction, and reduces post-SLT inflammation & discomfort.

Biography :

Leyla Ali Aljasim MD, FRCS Glasgow, Jordanian board of specialty- ophthalmology. Consultant at King Khaled eye specialist hospital, glaucoma division. Interested in Genetic studies of glaucoma, glaucoma medical treatment, LASER applications in glaucoma & the impact of having glaucoma on patients’ quality of life.

E-mail: ldjasim@kkesh.med.sa