Virology & Mycology
Open Access
ISSN: 2161-0517
+44 1223 790975
ISSN: 2161-0517
+44 1223 790975
Angelica Constanta Visan, Adrian Streinu Cercel, Anca Draganescu, Anuta Bilasco, Magdalena Vasile, Diana Slavu and Monica Luminita Luminos
ScientificTracksAbstracts-Workshop: Virol-mycol
Supervising influenza infections constitutes a priority for the health authorities in Romania and The National Institute of Infectious Diseases �??Professor Doctor Matei Bal�?�?? (INBI Matei Bals) in Bucharest assigns a particular attention to both the investigation and the treatment of patients suffering from influenza. In the last three years, the circulation of influenza viruses has registered important variations. In the 2012-2013 season, the A and B influenza infections have been present in equal proportions whereas in the 2013-2014 season, the influenza A virus was the dominant one (influenza A-95% cases/influenza B-5% cases). In the 2014-2015 season, until the end of March 2015, the influenza B virus dominated in a proportion of approximately 70% causing sever forms of illness by comparison to previous years. Within the department for children of INBI Matei Bal�?, patients were diagnosed using rapid tests (point-of-care) MARI-POC-Respi-test and both the confirmation and monitoring of the treatment were achieved with the use of molecular tests. Despite the fact that the recommendations of the features of the antiviral product-oseltamivir- assigns five days of treatment, successive determinations of RNA of the influenza infection by PCR, research has indicated that the virus remains positive more than ten days within most of the patients (75%). We cannot state to what extent the phenomenon has clinic repercussions, for instance, either by the risk of a relapse if the treatment is discontinued or strictly because of epidemiologic implications by maintaining the inter human transmission and consequently, the risk of developing a resistance to oseltamivir. We noticed that patients with highly persistent influenza virus in respiratory secretions had more severe forms of infection: Poliradiculoneuritis, encephalitis or myelitis. Therefore, we have taken into account extending the length of the antiviral treatment, a recommendation that could result in the avoidance of severe forms of illness as well as in a decrease in the number of secondary cases.
Angelica Constanta Visan is a PhD in Medical Sciences, primary MD in The National Institute of Infectious Diseases �??Matei BALS�??�?? in Bucharest at the Intensive Care unit for children and also highly experienced in the treatment of nervous system infections. At the same time, she is also a University Lecturer at �??Carol Davila�?� University of Medicine and Pharmacy in Bucharest. She has published extensive articles and held lectures on viral encephalitis giving particular attention to influenza-determined manifestations.