Hepatitis B and C infections among injecting drug users in Istria | 6081
Virology & Mycology

Virology & Mycology
Open Access

ISSN: 2161-0517

Hepatitis B and C infections among injecting drug users in Istria County, Croatia

6th Euro Virology Congress and Expo

March 10-12, 2016 Madrid, Spain

Jasmina Kucinar, Tatjana Vilibic-Cavlek, Lorena Lazaric-Stefanovic, Jasna Valic and Branko Kolaric

Istria County Institute of Public Health, Croatia
Croatian National Institute of Public Health, Croatia
University of Zagreb, Croatia
Teaching Institute of Public Health ├ó┬?┬?Dr Andrija Stampar├ó┬?┬Ł, Croatia
University of Ri

Posters & Accepted Abstracts: Virol-mycol

Abstract :

Aim: The aim of the study was to analyze the prevalence and some risk factors for contracting hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Istria County. Patients & Methods: 49 IDUs from Istria, the largest Croatian peninsula were tested in 2014 for the presence of hepatitis B surface antigen (HBsAg), hepatitis B core total antibodies (Anti-HBc) and hepatitis C virus antibodies (Anti-HCV). Study participants were recruited from the counseling center at the Istria County Institute of Public Health. Serologic tests were performed using an enzymelinked fluorescent assay. Anti-HCV repeatedly reactive samples were further confirmed using a third generation line immunoassay. Results: The overall prevalence of HBsAg, anti-HBc and anti-HCV was 2%, 38.8% and 75.5%, respectively. Male participants predominated (81.6%). Most of the participants clustered in the 30-49 years age group (83.6%). Prevalence of anti-HBc antibodies increased progressively with age starting sharply with 30 year olds (p=0.008). Sharing injection equipment correlated with HCV infection. Higher seroprevalence rates were found in IDUs who shared occasionally/frequently injection equipment than in participants that did not report sharing (anti-HCV 88.9%/66.7% vs. 57.9%, p=0.049). Results of the logistic regression showed that sharing injection equipment was a significant risk factor for HCV infection (IDUs who shared equipment occasionally: OR=4.32, 95% CI=2.28-8.20; AOR=4.6, 95% CI=2.21-9.57, IDUs who shared equipment frequently: OR=17.11, 95% CI=6.72-46.99; AOR=21.18; 95% CI=7.27-61.64). Conclusion: HBV and HCV infections are widespread among IDUs in Istria. Older age correlated strongly with HBV infection, while sharing injection equipment was the main risk factor for HCV infection.

Biography :

Jasmina Kucinar was graduated from the School of Medicine, University of Zagreb in 1991 and became a Specialist in Medical Microbiology and Parasitology in 2000. She has worked at the Microbiology Service of Istria County Institute of Public Health as Head of the Serology and Immunology Laboratory.


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