Journal of Clinical Trials
Open Access

Evaluation of palatability of a Metronidazole-based oral suspension in dogs when poured on the food and at different stages of shelf-life

5^th World Congress on Advanced Clinical Trials and Clinical Research

May 14-15, 2018 Singapore

Nicolas Celine, Martins F, Pujol C

Virbac, Carros, France

Posters & Accepted Abstracts: J Clin Trials

Abstract :

Metronidazole is the treatment of choice for Giardiasis in dogs. Compared to tablets, oral suspensions, when palatable, can be more convenient and allow a more precise dosing. The objective of this study was to assess the palatability of a new metronidazole-based oral suspension for dogs (Eradiaâ�?¢, Virbac) when poored on pet food and at different stages of the shelflife. Groups of 30 dogs received 25 mg/kg of the suspension, twice a day for 5 days, poured on 30 g of kibbles. Four different samples of the product were tested, depending on shelf-life: the first sample was used after production (T0), two other samples had been kept for 6 months before use, either at 25�?°C (T6M/25�?°C) or at 40�?°C (T6M/40�?°C) and the last one had been kept for 15 months at 25�?°C (T15M/25�?°C). Intake and consumption of the kibbles with product (or without product as a reference) were evaluated in each dog.All dogs took the kibbles with the products, independently of the batch used (100% intake). In terms of consumption, 90% of dogs totally consumed the kibbles poured with the batches T0 or T15M/25�?°C and 86.7% and 80% consumed the kibbles with the batches T6M/25�?°C and T6M/40�?°C, respectively. The rest of the dogs consumed the kibbles partially. As a control, 100% of dogs took and consumed the 30g kibbles without product. Therefore, this metronidazole-based oral suspension (Eradiaâ�?¢, Virbac) was very well accepted by dogs when poured of the food.

Biography :

Céline Nicolas graduated in Veterinary Medicine and as a PhD from the University of Nantes (France). She then worked as a Post-doctoral fellow and Research Assistant at the University of Bristol (UK) for 5 years and at the University of Nice (France) for 2 years. She has published a dozen articles in reputed journals and joined Virbac Medical department in 2016.
Email:celine.nicolas@virbac.com