Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Ashwag Almosa
King Saud University, Saudi Arabia
Scientific Tracks Abstracts: J Clin Exp Ophthalmol
Purpose: Long-term mitomycin C (MMC) effects in photorefractive keratectomy (PRK) were compared in simple myopic and astigmatic patients. Methods: In this observational cohort study, subjects were selected based on preoperative and postoperative data collected from medical records; they were divided into simple myopia with/without MMC and myopic astigmatism with/without MMC groups. Haze, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), subjective refraction, and K- reading were evaluated at 1-, 3-, 6-, and 12-month follow-ups. Results: One-hundred-fifty-nine eyes of 80 subjects (34 women and 46 men; mean age, 26.81 �?± 7.74 years; range, 18â�?�?53 years; spherical powers, -0.50 to -8.00 DS; cylindrical powers, -0.25 to -5.00 DC) were enrolled. One year postoperatively, the simple myopia with/without MMC groups showed no difference in UCVA (P = 0.187), BCVA (P = 0.163), or spherical equivalent (P = 0.163) and a significant difference (P = 0.0495) in K-reading; the haze formation difference was non-significant (P = 0.056). Astigmatic groups with/without MMC showed a significant difference in K-reading (P < 0.0001). MMC groups had less haze formation (P < 0.0001). Conclusion. PRK with intraoperative MMC application showed excellent visual outcomes. MMCâ�?�?s effect on astigmatic patients was significantly better with acceptable safety and minimal side effects.