Clinical approach to chronic relapsing inflammatory optic neuropa | 50669
Journal of Clinical and Experimental Ophthalmology

Journal of Clinical and Experimental Ophthalmology
Open Access

ISSN: 2155-9570

Clinical approach to chronic relapsing inflammatory optic neuropathies

3rd International Conference on Clinical & Experimental Ophthalmology

April 15-17, 2013 Hilton Chicago/Northbrook, USA

A Umur Kayabasi

AcceptedAbstracts: J Clin Exp Ophthalmol 2013

Abstract :

Chronic relapsing inflammatory optic neuropathy ( CRION ) is a recurrent optic neuropathy which is steroid sensitive. CRION is usually bilateral, often with pain and the magnetic resonance imaging (MRI) of the brain is normal while MRI of the optic nerves with contrast usually shows enhancement of the nerves, but not always. Laboratory work up is non- contributory and an underlying autoimmune disease can not be diagnosed. We describe our experience with six cases, five of whom were women and one man. The age ratio was between 27 and 54. All the patients had recurrent attacks of optic neuropathy on either side and all the attacks were sensitive to steroids. Because of the side effects of steroids , we had to use other immunosuppressants along with steroids. Three patients responded well to azathioprine and the dose of the steroids could be tapered. One patient, although had given response to oral prednisone before, could only have improvement in her vision after plasmapheresis. The male patient responded to steroids , but not to other classical immunosuppressants. His symptoms could be taken care of with infliximab. The treatment of patients with CRION is not easy and the risk/ benefit ratio of each medication should be weighed carefully. Especially in the case of infliximab, although it is a very powerful immunosuppressant, it can cause optic neuritis as a side effect

Biography :

A Umur Kayabasi is a graduate of Istanbul Medical Faculty. After working as an assistant in Ophthalmology, he completed his clinical fellowship program of Neuro- ophthalmology and electrophysiology at Michigan StateUniversity in 1995. After working as a consultant neuro- ophthalmologist in Istanbul, he worked at Wills Eye Hospital for 3 months as an observer. He has been working at World Eye Hospital since 2000. He has chapters in different neuro- ophthalmology books, arranged international symposiums, attended TV programs to advertise the neuro- ophthalmology subspecialty. He has also given lectures at local and international meetings, plus published papers in neuro ophthalmology.