Sequential Therapy with Tenofovir Plus Peg Interferon Enhances Innate and Adaptive Immunity Compared to Tenofovir Monotherapy in Chronic Hepatitis B Patients

Nirupma Trehanpati^1*, Arshi Khanam¹, Syed Hissar¹, Rashi Sehgal¹, Ritu Khosla¹, Paul David¹, Ashish Kumar¹, Anupama Prashar¹, Ankit Bhardwaj², Shyam Kottilil³ and Shiv Kumar Sarin^2*

¹Department of Research, Institute of Liver and Biliary Sciences, New Delhi, India, E-mail: akhanam@ihv.umaryland.edu

²Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India, E-mail: akhanam@ihv.umaryland.edu

³Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA, E-mail: akhanam@ihv.umaryland.edu

^*Corresponding Author(s): Dr. Nirupma Trehanpati, Institute of Liver and Biliary Sciences (ILBS), New Delhi – 110070, India, Tel: +91-11-46300000, Fax: +91-11- 26123504 Email: Professor Shiv Kumar Sarin, Institute of Liver and Biliary Sciences (ILBS), New Delhi – 110070, India, Tel: +91-11-46300000, Fax: +91-11- 26123504 Email: