Prostate Cancer Chemoprevention Targeting Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) and Atypical Small Acinar Proliferation (ASAP): Model for Trial Design and Outcome Measures

Aslam Kazi^1,2, Kyle Anderson¹⁰, Fred Schreiber⁹, Christopher R. Williams⁸, Tajammul Fazili⁷, Jerry McLarty⁶, Edouard Trabulsi⁵, Gregory Zagaja⁴, Mohamed Helal², Raoul Salup^2,3, Tian Chuang^1,2, Nagi Kumar^1,2*, Said Sebti^1,2, Michael Schell^1,2, Gwen Quinn^1,2, Kathleen Egan^1,2, Philippe E. Spiess^1,2, Julio Pow-Sang^1,2, Shahnjayla Connors^1,2, Tiffany Smith¹ and Theresa Crocker¹

¹Departments of Epidemiology, Health Outcomes and Behavior, Biostatistics, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida College of Medicine, Florida, USA, E-mail: nagi.kumar@moffitt.org

²Oncological Sciences, University of South Florida College of Medicine, Tampa Florida, USA, E-mail: nagi.kumar@moffitt.org

³James A. Haley V.A. Hospital, Tampa, FL, USA, E-mail: nagi.kumar@moffitt.org

⁴University of Chicago, Chicago, IL, USA, E-mail: nagi.kumar@moffitt.org

⁵Jefferson Medical College, Philadelphia, USA, E-mail: nagi.kumar@moffitt.org

⁶LSUHSC – Feist-Weiller Cancer Center, Shreveport, LA, USA, E-mail: nagi.kumar@moffitt.org

⁷Overton Brooks VA, Shreveport, LA, USA, E-mail: nagi.kumar@moffitt.org

⁸University of Florida – Jacksonville, USA, E-mail: nagi.kumar@moffitt.org

⁹Watson Clinic - Center for Cancer Care & Research, Lakeland, FL, USA, E-mail: nagi.kumar@moffitt.org

¹⁰Minneapolis VA Medical Center, Minneapolis, MN, USA, E-mail: nagi.kumar@moffitt.org

^*Corresponding Author: Nagi Kumar, Ph.D, RD, FADA, Professor, Department of Epidemiology, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida College of Medicine, 12902 Magnolia Drive Tampa, Florida 33612, USA, Tel: (813) 745-6885, Fax: (813) 745-7183 Email: