How does a 1.5-Fold Increase in Gene Dosage in Chromosome 21 Cause the Pleiotropic Phenotypes in Down Syndrome?

Baojin Ding^*

Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA

^*Corresponding Author: Baojin Ding, Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA, Tel: +1-508- 856-4415, Fax: +1-508-856-6266 Email: ,