Journal of Down Syndrome & Chromosome Abnormalities
Open Access

Down syndrome is a chromosome disorder associated with intellectual disability, a characteristic facial appearance, with small head and an upward slant to the eyes, and low muscle tone in infancy. They also have an increased risk to develop gastroesophageal reflux, celiac disease, hypothyroidism, hearing and vision problems, leukemia, and Alzheimer disease. People with Down Syndrome have fewer cells providing active surveillance in the immune system i.e., they would be having low immune power in their body by birth and they may mount immune responses more slowly than the general population. Because of all these factors, COVID 19 can be consider high risk to people with Down Syndrome. A number of children and adults who have Down syndrome will fall within these higher risk groups.