GET THE APP

Journal of Probiotics & Health

Journal of Probiotics & Health
Open Access

ISSN: 2329-8901

Research - (2021)Volume 9, Issue 7

Food Items Biologically Tailored to Meet Nutritional Deficiency Challenge during Covid 19 Pandemic

Faiza Abdur Rab*
 
*Correspondence: Faiza Abdur Rab, Department of Food Science and Technology, University of Karachi, Pakistan, Email:

Author info »

Abstract

Human body has its own mechanism to protect it from all type of illnesses including infectious one as well as from those which are no communicable including onset of metabolic syndrome and pre mature aging etc. Food intake governs the health status and illness history of individuals including the aging onset. This piece of work covers preparation details of certain Naturally Fortified Healthy Foody Drinks and Preparations built upon classical understanding of knowledge integrated with latest advancement in health sciences regular intake of which can not only delay the process aging, improves skin and hair texture but also ensures natural health with having therapeutic potential. These naturally fortified Foody items including Remedial Egg Mix are tailored by minimal processing at domestic level to meet nutritional deficiency challenge during Covid 19 Pandemic. Detailed discussion on this aspect of health related issues would be avoided as a chapter co-authored by me covering the topic of food driven tourism while discussing certain drivers of natural health using un reported novel approach based understanding on health sciences is already in press. This study can be used to design small business functional units helpful to deal with the various challenges of prevailing in present era of Covid 19 pandemic Functional food fermentation cheap raw produces diseases health food safety food supply chain microbiome probiotics food safety phytochemicals fortification, epigenetics SOD1 GSH, glucose metabolism cholesterol metabolism Covid 19 Nutritional deficiency challenge.

Keywords

Metabolism; Nutrition; Cholesterol metabolism; Microbiome; Probiotics.

Introduction

Food intake provides body with different metabolites nutrients beneficial microbes and also metabolites produced by them and energy only in case if these biological entities are absorbed in intestine or skin to enter in the blood from where through circulation directly or after having processed in concerned organ or tissues they reach to the targeted cells to interact or to enter in them to perform the specific functions or to convert into energy or/and to waste. The digestibility absorption potential product stability and the safety of minimally processed natural food and naturally fermented food are considerably higher than most of the processed food manufactured at industrial level in bulk quantity with having a shelf life depending on storage conditions and type of food product. Food intake governs the health status of individuals in addition to providing protection from all type of illnesses beside having therapeutic potential but at the same time food can be the key modulator for initiating different illnesses including pre mature aging as well as fatal diseases leading to death. Yeast genome shares remarkable gene conversation of gene functions with the human genome; greater than 40% of deciding the fate of cells and as well as the fate of living entity, Finding in yeast are consistent with human studies supporting the approach that food can initiate, protect and cure diseases also modulating the cellular functions including their fate regulated at genes network level e.g. a clinical link between vitamin E administration, cellular magnesium, GSH1 SOD1 GSH/GSSG ratio, sod1p, glutathione and tissue glucose metabolism and the plasma GSH/GSSG ratio seems to play a major role in the modulation of glucose homeostasis mainly in diabetics and modulate the aging process. Sod1p, glutathione including different antioxidants are basic ingredient of several natural raw produces other unprocessed food items and naturally fermented products. As mentioned earlier as well, further discussion on this aspect of health related issues would be avoided as a chapter co-authored by me revealing further details on this domain of knowledge is already in press and in other upcoming papers[1-110].

Fruits and fresh fruit juices (fruits extracts) are highly beneficial for health [8-17,27,34, 36,37,40-45,57,68,71-75]. Following are given a few Healthy Foodie Recipes along with some basic details.

Naturally Fortified Mango Fruity Juice

Mango is a fruit rich in vast range of nutrients fiber vital metabolites etc. which is widely available in many countries at reasonable cost. The biological potentials of Unripe Green Mangoes (Raw Mangoes) are yet to be revealed whereas its marketability as a produce and its biologically processed products can boost its trade globally. The Unripe Green Mangoes on keeping them in jute or cotton clothes at warm place ripe in natural manner within very short time with having improved organoleptic properties [21,50-54].

Take unripe 2-3 Unripe Green Mangoes (Unripe Raw Mangoes) peel them off by using a clean sharp knife and cut them into small pieces. Add around 1-2 table spoon salt and leave the in a glass vessel for around 2-3 hours at room temperature [8,9,11,111-124].

These salted Unripe Green Mango pieces can be stored under frozen conditions for up to six months for purpose of preparing juice. To prepare Naturally Fortified Mango Foody Juice, add salted Unripe Green Mango pieces into a vessel add sugar (2-3 table spoon brown or while sugar or honey depending on the desired taste) and leave it at room temperature for 2-3 hours [8,9,83,115-119,121,123].

Put them in commonly used domestic blender jug and pour around 200 mil potable water in blender. To give an aromatic touch adds small peeled off pieces of ripe Fresh Mango (around half mango) in the blender. Blend the content for 30 seconds at least for 7 time with having 1 minute intermediate break. Pour the Freshly Prepared Natural Mango Fruity Juice into a properly clean glass container make up volume upto 1 Litre [83,115,117,119,121,124-130] and store it under refrigerated condition until use. Naturally Fortified Mango Fruity Juice can be stored under refrigerated conditions for 24 hours. [7-11,26,37,38,75,104,111-132]. Mix well before serving. Serve Natural Mango Fruity Juice with crushed ice.

To confer laxative property in Naturally Fortified Mango Fruity Juice add a pinch of Himalayan Black Salt [133] in the juice prepared with having added the fresh ripe mango pieces and drink at least two glasses of it per day each about half an hour before meal.

Naturally Fortified Grewia Fruity Juice

Grewia (Grewia asiatica) is widely available in a few Asian countries including Pakistan and India. This fruit is rich in nutrients fiber and metabolites with having low calorie and fat. The key limitation in marketability of this produce and its naturally processed products is its limited shelf life even at refrigeration conditions [48,49].

Take around 1 kg fresh Grewia, wash them with potable water by dipping them in it followed by removing the dirty water by transferring the Grewia settled at the bottom of the vessel to a new glass vessel. Repeat this process 3-4 times. Make five portions of 1 kg Grewia put them in properly washed glass container and freeze them until use. Grewia can be stored under frozen conditions for up to two months while sustaining the organoleptic properties.

Put 1 portion of fresh/thawed Grewia in a glass container. Add 1/2 to 1 tea spoon salt and mix it well. Leave Grewia mixed with salt at room temperature for around an hour [8,9,117, 121-124,128,129].

Add 2-3 table spoon grinded sugar/honey in the Grewia Mix and mix the content well and leave it at room temperature for 1-2 hours [8,9,83,115-117,119,121,123,124].

Add fresh lemon juice extracted from squeezing 1 lemon, mix the content well and leave it for 30 minute Pour Grewia Mix [23,120]. Into commonly used domestic blender jar and add around 250 ml potable water and 2 pinch of black pepper [134,135] and blend it for about 9 times each for 30 seconds with having 1.5 minutes interval .Make up the volume up to 1 Litre [83,115,117,119,121,124,126, 130]. Pour Freshly Prepared Naturally Fortified Grewia Fruity Juice in a clean glass container to store up under refrigeration conditions until use [7-11,26,37,38,75,104-132]. Naturally Fortified Grewia Fruity Juice can be stored at refrigeration conditions for one day. Mix well and hold the content for 1 minute before pouring in glasses before serving. Serve Naturally Fortified Grewia Fruity Juice with crushed ices .To improves the laxative property of Freshly Prepared Natural Grewia Fruity Juice, add 1 pinch of Black Himalayan Salt [133] in the glass and drink 1-2 glasses of the Naturally Fortified Grewia Foody Juice per day each 1-2 hours before meal.

Natural Water Melon Fruity Juice

Water Melon is rich in nutrients fiber metabolites and a good source of water to keep body hydrated particularly in summer. It is very cheap and can be a healthy nourishing food for poor particularly in summer [39,136].

Take around 1/2 Kg of ripe watermelon cut into small pieces .and sieve it through wet Muslin cloth helpful to separate solid content having fiber seeds from its juice. Collect the juice into a glass container and add all the solid content after removing seeds. Pour the mixture into commonly used domestic blend Add 1/4 tea spoon salt [8,9,121,122,124] and sugar (white,sugar(or)brownsugar(or)honey[8,9,83,115,117,119,121,124,126, 130] as per desired taste and blend it for 5 times each for around 30 sec with having an in between interval of 1.5 minutes .Make up the volume up to 1 Litre and pour Freshly Prepared Natural Water Melon Juice into clean glass container to store until use [8,9,11,38,45,71-73,75,83,115-117,119,126,130,136-139].

Natural Water Melon Fruity Juice can be stored under refrigeration conditions for up to 1day.Mix well before serving it. Serve Natural Fruity Water Melon Juice with crushed ice.

To add the laxative property to Freshly Prepared Water Melon Fruity Juice, add 1 pinch of Black Himalayan Salt [133] in the glass and drink 1 glass of the Foody Juice 1-2 hours before meal.

Natural Cantaloupe, Honey Dew Melon, Musk Melon/Melon Juice

Cantaloupe, Honey Dew Melon Musk Melon/Melon is rich in fiber; metabolites nutrients etc and provide a healthy source of energy for being naturally sweet when properly ripened [44-47] is.Take 1 Cantaloupe, Honey Dew Melon Musk Melon/Melon fruit, peel it off and cut it into small pieces. Put the pieces into commonly used domestic blender and add around 150 ml of potable water into it. . Usually Cantaloupe, Honey Dew Melon Musk Melon /Melon is naturally sweet so there is no used to add sugar (white or brown) or honey in it. However in case if the fruit is not optimum ally ripened add 1-2 teaspoon sugar (white or brown) or honey [83,115-117,119,121,124,126,130] in it Blend it for 5 times each for around 30 sec with having an in between interval of 1.5 minutes. Make up the volume of Freshly Prepared Natural Cantaloupe, Honey Dew Melon/Melon Juice up to 1 Litre and pour it into a clean glass container to store it under refrigeration conditions until use [8,9,11,38,45,71- 73,75,83,115-117,119,126,130,136-139]. Natural Cantaloupe, Honey Dew Melon Musk Melon /Melon juice can be stored under refrigeration for 1 day. Stir well before serving. . Serve Natural Cantaloupe, Honey Dew Melon Musk Melon /Melon Juice with crushed ice.

Tip to Enhance the Mouth Feel and to Beat the Hunger

Apart of providing an excellent source of nutrition, metabolites fiber etc with instant energy and to hydrate the body in healthy manner, intake of these Natural Foody Juices/Freshly Prepared Naturally Fortified Foody Juices can delay the hunger and enhance tummy full feel by virtue of its rich solid content that includes fiber as well and decrease the rate of absorption of energy providing nutrients beside protecting the human body from experiencing glycemic index s spike, a consequence which triggers cascades of many interdependent manifestations leading to illness syndromes. The potential of Natural Fruity Juices to give mouth feel and to beat hunger while heightening their healthiness 3-5 table spoon of basil seeds [140-143] are added in Freshly Prepared Natural Foody Juices / Freshly Prepared Naturally Fortified Foody Juices and they are stored under refrigeration condition for 3-5 hours before serving them.

Remedial Egg Mix-Tip to Manage the Problem of Insomia

These days, during Covid 19 Pandemic insomnia is a common problem [144-147] problem.

Inappropriate intake of diet stress and extensive use of IT gadgets are generally the common cause of insomnia. To have proper sleep it is important to stop working on IT gadgets at least three hours before going to bed [146-149].

Regular intake of healthy food e.g.Freshly Prepared Naturally Fortified Fruity Juices and Remedial Egg Mix are proven to be helpful to improve the sleep duration and its quality beside maintain good health, protecting from diseases and curing them in natural manner [11,12,23,25,26,38,68-73,75-78,110,136-138,150-156].

Remedial Egg Mix taken around 1-2 hours before sleep also helps to have uninterrupted prolong sleep. To prepare Egg White Rich Fried break 4-5 eggs in a glass container leave 1-2 egg yolk and remove all of rest egg yolks. Add 1-2 pinch salt in it. Beat the egg content well for 2-3 minutes. Put half table spoon oil (maize or corn) or butter (1/2 teaspoon) and spread it well on non-sticking fry pan before pouring egg content into it. Leave it for 20-30 seconds until the lower side of egg content coagulates well. Turn the coagulated egg content down and cook up to desired organoleptic qualities [76-78,155-158].It is advisable to consume eggs of grains fed hens those have never been administrated any hormones.

Naturally Fortified Fruits Salad

Naturally Processed Fruits Salad is rich in nutrients metabolites fiber etc. and a good source of beneficial microbes and their metabolites. Regular intake of Naturally Fortified Fruits Salad up to 2-3 times a day helps to regain natural prolong sleep maintain good health besides protecting from many diseases and also provides their natural cure [4,7-17,23,27,34,38,40,43,57,68-70,73,101, 104,110,111,136-138,159-162].

To prepare Naturally Processed Fruits Salad Take 1 melon/honey dew melon/musk melon [44-47], 1/2 papaya [33,162] 3 apples [41,42], 3-4 banana [18-22], 2-3 guava [31,32,35-37], 3-4 oranges [23-26] and 2-3 know [23-26,162-164]. Peel off only papaya melon/honey dew melon oranges and kinnow. Cut all the fruits except Oranges and Know into small pieces (3-5 cm).Put 1/2-1 Teaspoon spoon salt and 1 pinch of Himalayan Black Salt [133] mix the content well into a glass container and leave the content at room temperature for 2-3 hours [8,9,35,38,117,121-124,128,129,164-166]. Add 1-2 Table spoon sugar (while or brown) or honey, mix well and leave the content at room temperature for 1 hour [8,9,35,37,38,41,83,115,117,119,121,123,124,126,129,130]. Add Kino freshly hand squeezed Kino and Orange Juice into it along with the remaining solid content after removing them from their attached peels [24-26]. Add around 1/4 to 1/5 Teaspoon Black Pepper [134,135] in the content and mix it well. Add Amchoor (dried green mango powder) [21,50-54], Tamarind extract ( Dip pulp of fruit of Tamarind in water for 20 minutes, remove seeds and solid content and pour the juice into Naturally Processed Fruits Salad) [28,29] Chat Ka Masala (a spices mixture containing coriander seeds Cumin seeds thymol mango powder Himalyian Black Salt mint leave powder cannamon funnel seeds star anise mace black cardamons green cardamons) [14,15,43,135,159,160,167-176] or berries pulp e.g. fresh strawberry pulp [55,56,153] into it as per need to attain desired taste and mix it well with fruit salad content. 1-2 Table spoons of basil seeds [140-143] can also be added to Naturally Fortified Fruits Salad followed by holding 2-3 hours under refrigeration conditions to enhance mouth feel and tummy fullness The Naturally Fortified Fruits Salad can be stored under refrigeration conditions for about 15 to 18 hours. Naturally Fortified Foody drinks Remedial Egg Mix and Naturally Fortified Fruits Salad are not only rich in nutrients metabolites fiber etc but are also a source of beneficial microbes and their metabolites with having improved nutritional digestibility absorption therapeutic potentials while having augmented safety and security as the Naturally Fortified Food Products hence these products governs the health status mind wellbeing and aging process in individuals regularly consuming them unlike the processed diet which is unhealthy and can initiate different illness on regular consumption[1-29,31-45,48-59,68-75,78,99,104,110,111,114,116,118, 124-126,128,129,131,132,134-136,138-140,147-148,150-153,156-160, 162-164,166-176].

In this era of Covid 19 Pandemic, globe has gone through massive transformation leading to disruption in food supply chain beside huge number of fatalities due to Covid 19 virus causing health manifestations in addition to adversely affecting the whole trade and transportation operations across the world making nutritional availability to sustain health and combat diseases among populations a depreciating factor particularly against Covid 19 infection has emerged as a big challenge all over the world [177-181]. Under this situation Naturally Fortified Food.

Products and Remedial Egg Mix prepared as described earlier provide a viable option to nourish global populations within limited available resources facilities and manpower.

Covid 19 vaccines available so far partly confers protection against limited Covid 19 variants for short duration with having health concerns including some serious ones beside ethical issues e.g. half of the genome of the virus is from avian origin and rest half is originated from bat origin making vaccine unacceptable for certain followers of various religious ideology [181-190].

Various food preparations are proven not only to protect the individuals from Covid 19 illness but also diminish illness manifestation and decrease the number of fatalities [23,85,132,175,190].

Since there has been incidences of bird flu virus infection among hens in Pakistan, there has been a salient decrease of Covid 19 prevalence numbers all over the country where poultry particularly chicken curry and eggs are present in daily main course of meal providing cross immunity against Covid 19 infection and needed nutritional supplementation indicating that oral vaccine against Covid 19 would be very likely more effective to confer protection. This study can be used to design small business functional units helpful to deal with the various challenges of prevailing in present era of Covid 19 pandemic [177,178,188-190].

As mentioned earlier as well, further discussion on this aspect of health related issues would be avoided as a chapter co-authored by me revealing further details on this domain of knowledge is already in press and in other upcoming papers [109].

Discussion

This piece of work is built upon present status of knowledge to evolve various novel food systems having enriched with nutrients metabolites microbes organoleptic and therapeutic potentials through naturally processing at domestic level in cost effective manner using locally available cheap produces while conferring food safety and ensuring their security though their shelf life under refrigerated condition is extended only for 1 day but at the same time protecting the products from losing a wide range of metabolites and biological factors also responsible for their therapeutic potentials and beneficial for health but are unstable under vitro conditions[4,6,7,15,17,21,23-25,27,29,31,32,35,38,40,44,45,48,55, 68-72,74,85,103,104, 110,118,127,131,132, 135,137,139,140,148,150-153,156-159,162, 167,169,172].

Naturally fortified Foody items including Remedial Egg Mix are naturally tailored different integrated biological strategies including fermentation involving minimal processing at domestic level to meet nutritional deficiency challenge during Covid 19 Pandemic helpful to sustain health and mind wellbeing, protect from diseases and cure them while decreasing the fatality rate. Extended discussion on the work would be avoided as a chapter co-authored by the author covering certain relevant details is in press [109].

Conclusion

In simple words, this study based on classical understanding integrated with latest advancement in health sciences provides a globally applicable alternative for supply chain having incorporated with genomic manipulation potentials governed by latest biotechnological approaches which are expensive, requires huge investment resources and trained manpower in addition having more challenges and serious ethical and health concerns. This study can be used to design small business functional units providing options for making best use of available resources while adding value to them within limited facilities which in turn would job opportunities and help the world to cope with nutritional deficiency health challenges financial constrains avoiding the need of extensive processing and hi tech storage facilities particularly in this Covid 19 era.

References

  1. Kiela PR, Ghishan FK (2016) Physiology of Intestinal Absorption and Secretion. Best Pract Res Clin Gastroenterol  30 :145-59.
  2. Tahara Y, Shibata S (2014) Chrono-Biology, Chrono-Pharmacology, and Chrono-Nutrition. J Pharmacol Sci 124:320-35.
  3. Zhao J, Zhang X, Liu H, Brown MA, Qiao S (2019) Dietary Protein and Gut Microbiota Composition and Function. Curr Protein Pept Sci 20:145-154.
  4. Farré R, Fiorani M, Abdu Rahiman S, Matteoli G (2020) Intestinal Permeability, Inflammation and the Role of Nutrients. Nutrients.J Pharmacol Sci 12:1185.
  5. Maggini S, Pierre A, Calder PC (2018) Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. J Pharmacol Sci 10:15-31.
  6. Bruins MJ, Van Dael P, Eggersdorfer M (2019) The Role of Nutrients in Reducing the Risk for Non-communicable Diseases during Aging. Nutrients. J Pharmacol Sci 11:85.
  7. Holesh JE, Aslam S, Martin A (2020) In: Stat Pearls Treasure Island (FL): Stat Pearls Publishing Nutrients.J Pharmacol Sci 28:38-53
  8. Slavin  (2013) Fiber and Prebiotics: Mechanisms and Health Benefits. Nutrients. J Pharmacol Sci 225:17-35
  9. Fernandez MA, Marette A (2017) Potential Health Benefits of Combining Yogurt and Fruits Based on Their Probiotic and Prebiotic Properties. Adv Nutr 8:155-164.
  10. Henning SM, Yang J, Shao P, Lee RP, Huang J et al. (2017) Health Benefit of Vegetable/Fruit Juice-Based Diet: Role of microbiome. Sci Rep 7(1):21-67.
  11. Kashi DS, Shabir A, Da Boit M, Bailey SJ, Higgins MF (2019) The Efficacy of Administering Fruit-Derived Polyphenols to Improve Health Biomarkers, Exercise Performance and Related Physiological Responses Nutrients. J Pharmacol Sci 11 :23-89.
  12. Liu RH (2013) Health-Promoting Components of Fruits and Vegetables in the Diet. Adv Nutr 4 :38-92
  13. Kozłowska A, Szostak-Wegierek D (2014) Flavonoids--food sources and health benefits. Rocz Panstw Zakl Hig. 65(2):79-85.
  14. Kandaswami C, Lee LT, Lee PP, Hwang JJ, Ke FC (2005) The Antitumor Activities of Flavonoids. In Vivo. Erratum in: In Vivo 21:553
  15. Rodriguez-Casado A (2016) The Health Potential of Fruits and Vegetables Phytochemicals: Notable Examples. Crit Rev Food Sci Nutr 56:101-107.
  16. Gul K, Singh AK, Jabeen R (2016) Nutraceuticals and Functional Foods: The Foods for the Future World. Crit Rev Food Sci Nutr 56 :17-27.
  17. Falcomer AL, Riquette RFR, de Lima BR, Ginani VC, Zandonadi RP (2019) Health Benefits of Green Banana Consumption: A Systematic Review. Nutrients 11(6):12-22.
  18. Amini Khoozani A, Birch J, Bekhit AEA (2019) Production, Application and Health Effects of Banana Pulp and Peel Flour in the Food Industry. J Food Sci Technol  56 :548-559.
  19. Apostolopoulos V, Antonipillai J, Tangalakis K, Ashton JF, Stojanovska L (2017) Let's Go Bananas! Gren Bananas and their Health Benefits. Pril  Makedon Akad Nauk Umet Odd Med Nauki 38:147-151.
  20. Guo W, Rao G, Wen X (2021) Arabinogalactan in Banana Chemical Characterization and Pharmaceutical Effects. Int J Biol Macromol 167:1059-1065.
  21. Singh B, Singh JP, Kaur A, Singh N (2016) Bioactive Compounds in Banana and their Associated Health Benefits-A review. Food Chem 206:1-11.
  22. Bellavite P, Donzelli A (2020) Hesperidin and SARS-CoV-2: New Light on the Healthy Function of Citrus Fruits. Antioxidants (Basel) 9(8):742.
  23. Mallick N, Khan RA (2016) Antihyperlipidemic Effects of Citrus Sinensis, Citrus Paradisi, and their Combinations. J Pharm Bioallied Sci 8:112-8.
  24. Pereira-Caro G, Clifford MN, Polyviou T, Ludwig IA, Alfheeaid H et al (2020) Plasma Pharmacokinetics of (poly) Phenol Metabolites and Catabolites after Ingestion of Orange Juice by Endurance Trained Men. Free Radic Biol Med. 160:784-795.
  25. Fernández-Pachón MS, Medina S, Herrero-Martín G, Cerrillo I, Berná G, et al (2014) Alcoholic Fermentation induces Melatonin Synthesis in Orange Juice. J Pineal Res. 56(1):31-8.
  26. Rangarajan H, Elumalai A, Chidanand DV (2021) Traditional Fruits of South India: Bioactive Components and their Potential Health Implications in Chronic Diseases. J Food Biochem. 45(3):e1326.
  27. Ebifa-Othieno E, Mugisha A, Nyeko P, Kabasa JD (2017) Knowledge, Attitudes and Practices in Tamarind (Tamarindus indica L) use and Conservation in Eastern Uganda. J Ethnobiol Ethnomed 13(1):5.
  28. Nakchat O, Nalinratana N, Meksuriyen D, Pongsamart S (2014) Tamarind Seed Coat Extract Restores Reactive Oxygen Species through Attenuation of Glutathione Level and Antioxidant Enzyme Expression in Human Skin Fibroblasts in Response to Oxidative Stress. Asian Pac J Trop Biomed. 4:379-85.
  29. Ursini F, Maiorino M, Gregolin C (1986) Phospholipid Hydroperoxide Glutathione Peroxidase. Int J Tissue React. 8(2):99-103.
  30. Alvarez-Suarez JM, Giampieri F, Gasparrini M, Mazzoni L, Forbes-Hernández TY (2018) Guava (Psidium guajava L. cv. Red Suprema) Crude Extract Protect Human Dermal Fibroblasts against Cytotoxic Damage Mediated by Oxidative Stress. Plant Foods Hum Nutr. 73(1):18-24.
  31. Jiao Y, Hua D, Huang D, Zhang Q, Yan C (2018) Characterization of a New Heteropolysaccharide from Green Guava and its application as an α-glucosidase Inhibitor for the Treatment of Type II Diabetes. Food Funct. 9(7):3997-4007.
  32. Khadam S, Afzal U, Gul H, Hira S, Satti M, et al.  (2019) Phytochemical Screening and Bioactivity Assessment of Leaves and Fruits Extract of Carica Papaya. Pak J Pharm Sci 32(5):1941-1948.
  33. Slavin JL, Lloyd B (2012) Health Benefits of Fruits and Vegetables. Adv Nutr 3(4):506-16.
  34. Thaptimthong T, Kasemsuk T, Sibmooh N, Unchern S (2016) Platelet Inhibitory Effects of Juices from Pachyrhizus Erosus L. Root and Psidium Guajava L. Fruit: a Randomized Controlled Trial in Healthy Volunteers. BMC Complement Altern Med. 16:269.
  35. Zhang Z, Kong F, Ni H, Mo Z, Wan JB, et al. (2016) Structural Characterization, α-Glucosidase Inhibitory and DPPH Scavenging activities of polysaccharides from Guava. Carbohydr Polym. 25(144):106-14.
  36. Menezes CC, De Deus Souza Carneiro J, Borges SV, da Silva VS, Brigagão MR,et al. (2012) Development of Low-Calorie Guava Preserves with Prebiotics and Evaluation of their Effects on Carcinogenesis Biomarkers in Rats. Food Chem Toxicol. 50:19-24.
  37. Žuntar I, Petric Z, Bursać Kovačević D, Putnik P (2020) Safety of Probiotics: Functional Fruit Beverages and Nutraceuticals. Foods 9(7):947.
  38. Naz A, Butt MS, Sultan MT, Qayyum MM, Niaz RS (2014) Watermelon Lycopene and Allied Health Claims. EXCLI J 3(13):650-60.
  39. Huang HY, Chang CK, Tso TK, Huang JJ, Chang WW (2004) Antioxidant Activities of Various Fruits and Vegetables produced in Taiwan. Int J Food Sci Nutr 55(5):423-9.
  40. Skinner RC, Gigliotti JC, Ku KM, Tou JC (2018) A Comprehensive Analysis of the Composition, Health Benefits, and safety of Apple pomace. Nutr Rev 76(12):893-909.
  41. Boyer J, Liu RH (2004) Apple Phytochemicals and their Health Benefits. Nutr J 1(2):3-5.
  42. Williamson G (2017) The Role of Polyphenols in Modern Nutrition. Nutr Bull 42(3):226-235.
  43. Lester GE, Jifon JL, Crosby KM (2009) Superoxide Dismutase Activity in Mesocarp Tissue from Divergent Cucumis melo L. genotypes. Plant Foods Hum Nutr 64(3):205-11.
  44. Saby M, Gauthier A, Barial S, Egoumenides L, Jover B.(2020) Supplementation with a Bioactive Melon Concentrate in Humans and Animals: Prevention of Oxidative Damages and Fatigue in the Context of a Moderate or Eccentric Physical Activity. Int J Environ Res Public Health 17(4):1142.
  45. Lester GE (2000) Polyamines and their Cellular Anti-Senescence Properties in Honey Dew Muskmelon Fruit. Plant Sci 160(1):105-112.
  46. Menezes Ayres EM, Lee SM, Boyden L, Guinard JX (2019) Sensory Properties and Consumer Acceptance of Cantaloupe Melon Cultivars. J Food Sci 84(8):2278-2288.
  47. Mehmood A, Ishaq M, Usman M, Zhao L, Ullah A, et al. (2020) Nutraceutical Perspectives and Value Addition of Phalsa (Grewia asiatica L.): A review. J Food Biochem. 44(7):13228.
  48. Zia-Ul-Haq M, Stanković MS, Rizwan K, Feo VD (2013) Grewia asiatica L, a Food Plant With Multiple Uses. Molecules 18(3):2663-82.
  49. Maldonado-Celis ME, Yahia EM, Bedoya R, Landázuri P, Loango N, et al. (2019) Chemical Composition of Mango (Mangifera indica L.) Fruit: Nutritional and Phytochemical Compounds. Front Plant Sci 10:1073.
  50. Burton-Freeman BM, Sandhu AK, Edirisinghe I (2017) Mangos and their Bioactive Components: Adding Variety to the Fruit Plate for Health. Food Funct 8(9):3010-3032.
  51. Lebaka VR, Wee YJ, Ye W, Korivi M.(2021) Nutritional Composition and Bioactive Compounds in Three Different Parts of Mango Fruit. Int J Environ Res Public Health 18(2):741.
  52. Patiño-Rodríguez O, Bello-Pérez LA, Agama-Acevedo E, Pacheco-Vargas  (2020) Pulp and Peel of Unripe Stenospermocarpic Mango (Mangifera indica L. cv Ataulfo) as an Alternative Source of Starch, Polyphenols and Dietary Fibre. Food Res Int 138:109-719
  53. Alañón ME, Oliver-Simancas R, Gómez-Caravaca AM, Arráez-Román D, Segura-Carretero A (2019) Evolution of Bioactive Compounds of Three Mango Cultivars (Mangifera indica L.) at different Maturation Stages Analyzed by HPLC-DAD-q-TOF-MS. Food Res Int 125:108-526.
  54. Skrovankova S, Sumczynski D, Mlcek J, Jurikova T, Sochor J (2015) Bioactive Compounds and Antioxidant Activity in Different Types of Berries. Int J Mol Sci 16(10):24673-706.
  55. Afrin S, Gasparrini M, Forbes-Hernandez TY, Reboredo-Rodriguez P, Mezzetti B, et al. (2016) Promising Health Benefits of the Strawberry: A Focus on Clinical Studies. J Agric Food Chem 64(22):4435-49.
  56. Sun J, Chu YF, Wu X, Liu RH (2002) Antioxidant and Antiproliferative activities of Common Fruits. J Agric Food Chem 50(25):7449-54.
  57. Mazzoli A, Crescenzo R, Cigliano L, Spagnuolo MS, Cancelliere R, et al. (2019) Early Hepatic Oxidative Stress and Mitochondrial Changes Following Western Diet in Middle Aged Rats. Nutrients 11(11):26-70.
  58. Crescenzo R, Spagnuolo MS, Cancelliere R, Iannotta L, Mazzoli A et al. (2019) Effect of Initial Aging and High-Fat/High-Fructose Diet on Mitochondrial Bioenergetics and Oxidative Status in Rat Brain. Mol Neurobiol 56(11):7651-7663.
  59. Steinmeier J, Dringen R (2019) Exposure of Cultured Astrocytes to Menadione Triggers Rapid Radical Formation, Glutathione Oxidation and Mrp1-Mediated Export of Glutathione Disulfide. Neurochem Res 44(5):1167-1181.
  60. Valerius MT, Li H, Stock JL, Weinstein M, Kaur S, et al. (1995) Gsh-1: a Novel Murine Homeobox Gene Expressed in the Central Nervous System. Dev Dyn 203(3):337-51.
  61. Abudugupur A, Xu Z, Mitsui K, Hisaki H, Ueda N, et al.(2003) Severe Reduction of Superoxide Dismutase Activity in the Yeast Saccharomyces Cerevisae with the Deletion or Overexpression of GTS1. FEMS Microbiol Lett. 223(1):141-5.
  62. Brasil AA, Belati A, Mannarino SC, Panek AD, Eleutherio EC (2013) The Involvement of GSH in the Activation of Human Sod1 Linked to FALS in Chronologically Aged Yeast Cells. FEMS Yeast Res 13(5):433-40.
  63. Sturtz LA, Diekert K, Jensen LT, Lill R, Culotta VC (2001) A fraction of Yeast Cu,Zn-Superoxide Dismutase and its Metallochaperone, CCS, Localize to the Intermembrane Space of Mitochondria. A Physiological Role for SOD1 in Guarding against Mitochondrial Oxidative Damage. J Biol Chem 276(41):38084-9.
  64. Yang F, Pei R, Zhang Z, Liao J, Yu W,et al. (2019) Copper Induces Oxidative Stress and Apoptosis through Mitochondria-Mediated Pathway in Chicken Hepatocytes. Toxicol In Vitro. 54:310-316.
  65. Ursini F, Maiorino M (2020) Lipid Peroxidation and Ferroptosis: The Role of GSH and GPx4. Free Radic Biol Med 15(2):175-185.
  66. Tan SX, Teo M, Lam YT, Dawes IW, Perrone GG (2009) Cu, Zn Superoxide Dismutase and NADP (H) Homeostasis are required for Tolerance of Endoplasmic Reticulum Stress in Saccharomyces Cerevisiae. Molecular biology of the cell 20(5):1493–1508.
  67. Brookie KL, Best GI, Conner TS (2018) Intake of Raw Fruits and Vegetables Is Associated With Better Mental Health Than Intake of Processed Fruits and Vegetables. Front Psychol 9:487.
  68. Gianfredi V, Nucci D, Tonzani A, Amodeo R, Benvenuti AL, et al. (2018) Sleep Disorder, Mediterranean Diet and Learning Performance among Nursing Students: in SOMNIA, a cross-sectional study. Ann Ig 30(6):470-481.
  69. Firth J, Gangwisch JE, Borisini A, Wootton RE, Mayer EA (2020) Food and Mood: How do Diet and Nutrition Affect Mental Wellbeing? BMJ 36(9):23-82.
  70. Bakuradze T, Tausend A, Galan J, Groh IAM, Berry D, et al. (2019) Antioxidative Activity and Health Benefits of Anthocyanin-rich Fruit Juice in Healthy Volunteers. Free Radic Res 53(1):1045-1055.
  71. Durazzo A, Lucarini M, Novellino E, Daliu P, Santini A (2019) Fruit-based Juices: Focus on Antioxidant Properties-Study Approach and Update. Phytother Res 33(7):1754-1769.
  72. Ho KKHY, Ferruzzi MG, Wightman JD (2020) Potential Health Benefits of (Poly) Phenols Derived from Fruit and 100% Fruit Juice. Nutr Rev 78(2):145-174.
  73. Losso JN, Finley JW, Karki N, Liu AG, Prudente A, et al. (2018) Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. Am J Ther 25(2):194-201.
  74. Dimitrellou D, Solomakou N, Kokkinomagoulos E, Kandylis P (2020) Yogurts Supplemented with Juices from Grapes and Berries. Foods 9(9):1158.
  75. Wilson PB (2017) Recent Advances in Avian Egg Science: A Review. Poultry Science 96(10):3747–3754.
  76. Sun C, Liu J, Yang N, Xu G (2019) Egg Quality and Egg Albumen Property of Domestic Chicken, Duck, Goose, Turkey, Quail, and Pigeon. Poult Sci 98(10):4516-4521.
  77. López Sobaler AM, Aparicio Vizuete A, Ortega RM (2017) Papel Del Huevo En La Dieta De Deportistas Y Personas Físicamente Activas [Role Of The Egg In The Diet Of Athletes And Physically Active People]. Nutr Hosp 34(4):31-35.
  78. Rab FA (2007) Phenotypic Variation in Resistance Between The Individual Cells In Isogenic Populations Of Saccharomyces Cerevisiae. Mphil Thesis, University Of Nottingham UK 4(2):52-89
  79. Bishop AL, Rab FA, Sumner ER, Avery SV (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol  63(2):507-20.
  80. Rab FA (2014) Environmentally Modulated Evolution through Genetic Regulation ISB News Reports  1(3):15-25.
  81. Rab FA (2018)(a) Is Sugar an Accessory or Neccessary.EC Nutrition 13(4):236-237.
  82. Rab FA (2018)(b) Drug disease relationship and the role of food in healthy living.EC Nutrition 13.8
  83. Rab FA (2019)(b) Is hunger more dangerous than having malnutrtion or having unsafe diet.EC Nutrition 14(12):01-05
  84. Rab FA (2020)(b) Halal or Haram-New Challenges for Religious Scholars Muslim World and Food Supply Chain Stake Holders. Int J Nutr Sci & Food Tech 6:3.
  85. Nargund AM, Avery SV, Houghton JE (2008) Cadmium induces a heterogeneous and caspase-dependent apoptotic response in Saccharomyces cerevisiae. Apoptosis 13(6):811-21.
  86. Stratford M, Steels H, Novodvorska M, Archer DB, Avery SV (2019) Extreme Osmotolerance and Halotolerance in Food-Relevant Yeasts and the Role of Glycerol-Dependent Cell Individuality. Front Microbiol 9(9):32-38.
  87. Collinson EJ, Grant CM (2003) Role of yeast glutaredoxins as glutathione S-transferases. J Biol Chem 278(25):22492-7.
  88. Stratford M, Vallières C, Geoghegan IA, Archer DB, Avery SV (2020) The Preservative Sorbic Acid Targets Respiration, Explaining the Resistance of Fermentative Spoilage Yeast Species. mSphere. 5(3):73-20.
  89. Sumner ER, Shanmuganathan A, Sideri TC, Willetts SA, Houghton JE (2005) Oxidative protein damage causes chromium toxicity in yeast. Microbiology (Reading) 151(6):1939-1948.
  90. Bendjilali N, MacLeon S, Kalra G, Willis SD, Hossian AK, et al. (2017) Time-Course Analysis of Gene Expression During the Saccharomyces cerevisiae Hypoxic Response. G3 (Bethesda) 7(1):221-231.
  91. Avery AM, Avery SV (2001) Saccharomyces cerevisiae expresses three phospholipid hydroperoxide glutathione peroxidases. J Biol Chem 276(36):33730-5.
  92. Collinson EJ, Wheeler GL, Garrido EO, Avery AM, Avery SV (2002) The yeast glutaredoxins are active as glutathione peroxidases. J Biol Chem  277(19):16712-7.
  93. Smith MC, Sumner ER, Avery SV (2007) Glutathione and Gts1p drive beneficial variability in the cadmium resistances of individual yeast cells. Mol Microbiol  66(3):699-712.
  94. Sumner ER, Avery AM, Houghton JE, Robins RA, Avery SV (2003) Cell cycle-and age-dependent activation of Sod1p drives the formation of stress resistant cell subpopulations within clonal yeast cultures. Mol Microbiol 50(3):857-70.
  95. Reddy VS, Palika R, Ismail A, Pullakhandam R, Reddy GB (2018) Nutrigenomics: Opportunities & challenges for public health nutrition. Indian J Med Res 148(5):632-641.
  96. Talarico MCR, Nunes RAL, Silva GÁF, Costa LBED, Cardoso MR, et al. (2021) High Expression of SOD2 Protein Is a Strong Prognostic Factor for Stage IIIB Squamous Cell Cervical Carcinoma. Antioxidants (Basel) 10(5):724.
  97. Wallace TC, Bailey RL, Blumberg JB, Burton-Freeman B, Chen CO, et al. (2020) Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake. Crit Rev Food Sci Nutr 60(13):2174-2211
  98. Maggini S, Pierre A, Calder PC (2018) Immune Function and Micronutrient Requirements Change over the Life Course. Nutrients. 10(10):15-31.
  99. Bruins MJ, Van Dael P, Eggersdorfer M (2019) The Role of Nutrients in Reducing the Risk for Noncommunicable Diseases during Aging. Nutrients 11(1):85.
  100. Lee ES, Song EJ, Nam YD, Lee SY (2018) Probiotics in human health and disease: from nutribiotics to pharmabiotics. J Microbiol. 56(11):773-782.
  101. Foury F (1997) Human genetics diseases: crosstalk between man and yeast. Gene  19(5): 1-10.
  102. Paolisso G, Di Maro G, Pizza G, D'Amore A, Sgambato S, et al. (1992) Plasma GSH/GSSG affects glucose homeostasis in healthy subjects and non-insulin-dependent diabetics. Am J Physiol. 263(3):35-40.
  103. Barbagallo M, Dominguez LJ, Tagliamonte MR, Resnick LM, Paolisso G (1999) Effects of vitamin E and glutathione on glucose metabolism: role of magnesium. Hypertension 34(4):1002-6.
  104. Hassan A (2022) Handbook of Technology Application in Tourism in Asia Springer Nature (in Press).
  105. Wang L, Guo MJ, Gao Q, Yang JF, Yang L,et al. (2018) The effects of probiotics on total cholesterol: A meta-analysis of randomized controlled trials. Medicine 97(5):96-79.
  106. Markowiak P, Śliżewska K (2017) Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients 9(9):10-21.
  107. Li L, Wang L, Fan W, Jiang Y, Zhang C, et al. (2020) The Application of Fermentation Technology in Traditional Chinese Medicine: A Review. Am J Chin Med 48(4):899-921.
  108. D'Este M, Alvarado-Morales M, Angelidaki I (2018) Amino acids production focusing on fermentation technologies-A review. Biotechnol Adv  36(1):14-25.
  109. Solomons NW (2002) Fermentation, fermented foods and lactose intolerance. Eur J Clin Nutr. 56(4):50-5.
  110. Dashko S, Zhou N, Compagno C, Piškur J (2014) Why, when, and how did yeast evolve alcoholic fermentation? FEMS Yeast Res. 14(6):826-32.
  111. Ozen M, Dinleyici EC (2015) The history of probiotics: the untold story. Benef Microbes 6(2):159-65
  112. Liu C, Ren L, Yan B, Luo L, Zhang J (2021) Electron transfer and mechanism of energy production among syntrophic bacteria during acidogenic fermentation: A review. Bioresour Technol 323:124-637.
  113. Dimidi E, Cox SR, Rossi M, Whelan K (2019) Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease. Nutrients 11(8):1806.
  114. Walker GM, Walker RSK (2018) Enhancing Yeast Alcoholic Fermentations. Adv Appl Microbiol 105:87-129.
  115. Pan L, Chen XS, Wang KF, Mao ZG (2020) Mechanisms of response to pH shock in microbial fermentation. Bioprocess Biosyst Eng 43(3):361-372.
  116. Hartmann AL, Behrendt RA, Frøst MB (2019) Fermentation as a driver for food innovation. FEMS Microbiol Lett 366(6):058.
  117. Juturu V, Wu JC (2016) Microbial production of lactic acid: the latest development. Crit Rev Biotechnol 36(6):967-977.
  118. Arora S, Rani R, Ghosh S (2018) Bioreactors in solid state fermentation technology: Design, applications and engineering aspects. J Biotechnol 269:16-34.
  119. Altay F, Karbancıoglu-Güler F, Daskaya-Dikmen C, Heperkan D (2013) A review on traditional Turkish fermented non-alcoholic beverages: microbiota, fermentation process and quality characteristics. Int J Food Microbiol 167(1):44-56.
  120. Şanlier N, Gökcen BB, Sezgin AC (2019) Health benefits of fermented foods. Crit Rev Food Sci Nutr 59(3):506-527.
  121. Fiorda FA, de Melo Pereira GV, Thomaz-Soccol V, Rakshit SK, Pagnoncelli MGB (2017) Microbiological, biochemical, and functional aspects of sugary kefir fermentation-A review. Food Microbiol. 66:86-95.
  122. Jans C, Mulwa Kaindi DW, Meile L. Innovations in food preservation in pastoral zones. Rev Sci Tech 35(2):597-610.
  123. Murevanhema YY, Jideani VA (2013) Potential of Bambara groundnut (Vigna subterranea (L.) Verdc) milk as a probiotic beverage-a review. Crit Rev Food Sci Nutr 53(9):954-67.
  124. Simpson HL, Campbell BJ (2015) Review article: dietary fibre-microbiota interactions. Aliment Pharmacol Ther 42(2):158-79.
  125. Patidar MK, Nighojkar S, Kumar A, Nighojkar A (2018) Pectinolytic enzymes-solid state fermentation, assay methods and applications in fruit juice industries: a review 3 Biotech 8(4):199.
  126. Melini F, Melini V, Luziatelli F, Ficca AG, Ruzzi M (2019) Health-Promoting Components in Fermented Foods: An Up-to-Date Systematic Review. Nutrients 11(5):11-89.
  127. Alkhatib A (2020) Antiviral Functional Foods and Exercise Lifestyle Prevention of Coronavirus. Nutrients 12(9):2633.
  128. Chander V, Tewari D, Negi V, Singh R, Upadhyaya K (2020) Structural characterization of Himalayan black rock salt by SEM, XRD and in-vitro antioxidant activity. Sci Total Environ. 1(5):141-269.
  129. Butt MS, Pasha I, Sultan MT, Randhawa MA, Saeed F (2013) Black pepper and health claims: a comprehensive treatise. Crit Rev Food Sci Nutr 53(9):875-86.
  130. Sang TA (2019) Health Benefits of Culinary Herbs and Spices. J AOAC Int 102(2):395-411.
  131. Murray RD  (2020)100% Fruit Juice in Child and Adolescent Dietary Patterns. J Am Coll Nutr 39(2):122-127.
  132. Esteve MJ, Frígola A (2007) Refrigerated fruit juices: quality and safety issues. Adv Food Nutr Res 52:103-39.
  133. Benton D, Young HA (2020) Role of fruit juice in achieving the 5-a-day recommendation for fruit and vegetable intake. Nutr Rev 77(11):829-843.
  134. Manivannan A, Lee ES, Han K, Lee HE, Kim DS (2020) Versatile Nutraceutical Potentials of Watermelon-A Modest Fruit Loaded with Pharmaceutically Valuable Phytochemicals. Molecules 25(22):52-58.
  135. Rashid S, Zafar M, Ahmad M, Shinwari MI, Yaseen G, et al. (2019) Authentication of herbal drug Tukhm-e-balango (Lallemantia royleana Benth.) using microscopic, pharmacognostic, and phytochemical characterization. Microsc Res Tech. 82(6):731-740
  136. Abdollahi Mandoulakani B, Eyvazpour E, Ghadimzadeh M (2017) The effect of drought stress on the expression of key genes involved in the biosynthesis of phenylpropanoids and essential oil components in basil (Ocimum basilicum L.). Phytochemistry. 139:1-7.
  137. Samateh M, Pottackal N, Manafirasi S, Vidyasagar A, Maldarelli C (2018) Unravelling the secret of seed-based gels in water: the nanoscale 3D network formation. Sci Rep 8(1):73-15.
  138. Mostafavi S, Asadi-Gharneh HA, Miransari M (2019) The phytochemical variability of fatty acids in basil seeds (Ocimum basilicum L.) affected by genotype and geographical differences. Food Chem 27(6):700-706.
  139. Roth T (2007) Insomnia: definition, prevalence, etiology, and consequences. Journal of clinical sleep medicine: JCSM: official publication of the American Academy of Sleep Medicine, 3(5): S7–S10.
  140. Thomas SJ, Calhoun D (2017) Sleep, insomnia, and hypertension: current findings and future directions. J Am Soc Hypertens 11(2):122-129.
  141. Ramón-Arbués E, Martínez Abadía B, Granada López JM, Echániz Serrano E, Pellicer García B, et al. (2019) Conducta alimentaria y su relación con el estrés, la ansiedad, la depresión y el insomnio en estudiantes universitarios [Eating behavior and relationships with stress, anxiety, depression and insomnia in university students.]. Nutr Hosp 36(6):1339-1345.
  142. Zhao M, Tuo H, Wang S, Zhao L (2020) The Effects of Dietary Nutrition on Sleep and Sleep Disorders. Mediators Inflamm 2(2):142-874.
  143. Thomas SJ, Calhoun D (2017) Sleep, insomnia, and hypertension: current findings and future directions. J Am Soc Hypertens. 11(2):122-129.
  144. Gianfredi V, Nucci D, Tonzani A, Amodeo R, Benvenuti AL (2018) Sleep disorder, Mediterranean Diet and learning performance among nursing students: inSOMNIA, a cross-sectional study. Ann Ig 30(6):470-481.
  145. Firth J, Gangwisch JE, Borisini A, Wootton RE, Mayer EA (2020) Food and mood: how do diet and nutrition affect mental wellbeing? BMJ 1(1):369-2382.
  146. Ferri GM, Cavone D, Intranuovo G, Macinagrossa L (2019) Healthy Diet and Reduction of Chronic Disease Risks of Night Shift Workers. Curr Med Chem 26(19):3521-3541
  147. Losso JN, Finley JW, Karki N, Liu AG, Prudente A, et al.(2018) Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. Am J Ther 2 (2):194-201.
  148. Salehi B, Venditti A, Sharifi-Rad M, Kręgiel D, Sharifi-Rad J et al. (2019) The Therapeutic Potential of Apigenin. Int J Mol Sci 20(6):13-05.
  149. Meng X, Li Y, Li S, Zhou Y, Gan RY,(2017) Dietary Sources and Bioactivities of Melatonin. Nutrients 9(4):3-67.
  150. Mohajeri MH, Wittwer J, Vargas K, Hogan E, Holmes A, et al. (2015) Chronic treatment with a tryptophan-rich protein hydrolysate improves emotional processing, mental energy levels and reaction time in middle-aged women. Br J Nutr 113(2):350-65.
  151. Richard C, Cristall L, Fleming E, Lewis ED, Ricupero M (2017) Impact of Egg Consumption on Cardiovascular Risk Factors in Individuals with Type 2 Diabetes and at Risk for Developing Diabetes: A Systematic Review of Randomized Nutritional Intervention Studies. Can J Diabetes 41(4):453-463.
  152. López Sobaler AM, Aparicio Vizuete A (2017) Ortega RM. Papel del huevo en la dieta de deportistas y personas físicamente activas [Role of the egg in the diet of athletes and physically active people]. Nutr Hosp 34(4):31-35.
  153. Serafini M, Peluso I (2016) Functional Foods for Health: The Interrelated Antioxidant and Anti-Inflammatory Role of Fruits, Vegetables, Herbs, Spices and Cocoa in Humans. Curr Pharm De 22(44):6701-6715.
  154. Leitzmann C  (2016) Characteristics and Health Benefits of Phytochemicals. Forsch Komplementmed  23(2):69-74.
  155. Mazorra-Manzano MA, Ramírez-Suarez JC, Yada RY (2018) Plant proteases for bioactive peptides release: A review. Crit Rev Food Sci Nutr  58(13):2147-2163.
  156. Khalid S, Malik AU, Khan AS, Shahid M, Shafique M (2016) Tree age, fruit size and storage conditions affect levels of ascorbic acid, total phenolic concentrations and total antioxidant activity of 'Kinnow' mandarin juice. J Sci Food Agric 96(4):1319-25.
  157. Ilame SA, Singh SV (2018) Physico-chemical properties of ultrafiltered kinnow (mandarin) fruit juice. J Food Sci Technol 55(6):2189-2196.
  158. Septembre-Malaterre A, Remize F, Poucheret P (2018) Fruits and vegetables, as a source of nutritional compounds and phytochemicals: Changes in bioactive compounds during lactic fermentation. Food Res Int. 10(4) :86-99.
  159. Di Cagno R, Coda R, De Angelis M, Gobbetti M (2013) Exploitation of vegetables and fruits through lactic acid fermentation. Food Microbiol 33(1):1-10.
  160. Yu AO, Leveau JHJ, Marco ML (2020) Abundance, diversity and plant-specific adaptations of plant-associated lactic acid bacteria. Environ Microbiol Rep 12(1):16-29.
  161. Bower A, Marquez S, de Mejia EG (2016) The Health Benefits of Selected Culinary Herbs and Spices Found in the Traditional Mediterranean Diet. Crit Rev Food Sci Nutr 56(16):2728-46.
  162. Issaoui M, Delgado AM, Caruso G, Micali M, Barbera M et al.(2020) Phenols, Flavors, and the Mediterranean Diet. J AOAC Int. ;103(4):915-924.
  163. Ninfali P, Mea G, Giorgini S, Rocchi M, Bacchiocca M.(2005) Antioxidant capacity of vegetables, spices and dressings relevant to nutrition. Br J Nutr 93(2): 57-66.
  164. Tapsell LC, Hemphill I, Cobiac L, Patch CS, Sullivan DR, et al. (2006) Health benefits of herbs and spices: the past, the present, the future. Med J Aust 185(S4):S1-S24.
  165. Morgan AE, Mooney KM, Wilkinson SJ, Pickles NA, Mc Auley MT (2016) Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation. Ageing Res Rev 1(10):108-124.
  166. Rastogi S, Pandey MM, Rawat AKS (2017) Spices: Therapeutic Potential in Cardiovascular Health. Curr Pharm Des 23(7):989-998.
  167. Vázquez-Fresno R, Rosana ARR, Sajed T, Onookome-Okome T, Wishart NA,et al. (2019) Herbs and Spices-Biomarkers of Intake Based on Human Intervention Studies-A Systematic Review. Genes Nutr 2(2):14-18.
  168. Opara EI, Chohan M.(2014) Culinary herbs and spices: their bioactive properties, the contribution of polyphenols and the challenges in deducing their true health benefits. Int J Mol Sci 15(10):183-202.
  169. Isbill J, Kandiah J, Kružliaková N (2020) Opportunities for Health Promotion: Highlighting Herbs and Spices to Improve Immune Support and Well-being. Integr Med (Encinitas) 19(5):30-42.
  170. García-Casal MN, Peña-Rosas JP, Malavé HG (2016) Sauces, spices, and condiments: definitions, potential benefits, consumption patterns, and global markets. Ann N Y Acad Sci. 1379(1):3-16.
  171. Barrangou R, Notebaart RA (2019) CRISPR-Directed Microbiome Manipulation across the Food Supply Chain. Trends Microbiol  27(6):489-496.
  172. Barman A, Das R, Kanti De (2021) Impact of COVID-19 in food supply chain: Disruptions and recovery strategy Curent Research in Behavioral Sciences 11(7):66-82
  173. Dhama K, Khan S, Tiwari R, Sircar S Bhat S, et al. (2020) Coronavirus Disease 2019-COVID-19. Clinical microbiology reviews, 33(4):28-20.
  174. Sharma A, Ahmad Farouk I, Lal SK (2021) COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention. Viruses, 13(2):202.
  175. Tizaoui K, Zidi I, Lee KH, Ghayda RA, Hong H, et al. (2020) Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19). International journal of biological sciences, 16(15):2906–2923.
  176. Dawn (2020a). Ibuprofen and coronavirus: what is the connection-if any-according to health experts. Retrieved Trop Med Int Health 1(3):57-64.
  177. Dawn (2020b). Diet for Covid-19. Retrieved Trop Med Int Health 1(2):51-60
  178. Qing E, Gallagher T (2020) SARS Coronavirus Redux. Trends Immunol 41(4):271-273.
  179. Vela Ramirez JE, Sharpe LA, Peppas NA (2017) Current state and challenges in developing oral vaccines. Advanced drug delivery reviews 11(4):116–131.
  180. Wibawa T (2021) COVID-19 vaccine research and development: ethical issues. Trop Med Int Health 26(1):14-19.
  181. Rab FA (1995) “A Comparative Study of Immunological Protection Conferred by Certain Antigenic Preparations of Listeria Monocytogenes”. M.Sc Thesis submitted to University of Karachi Pakistan,Lycke. Recent progress in mucosal vaccine development: potential and limitations. Nat Rev Immunol 12(8):592-605.
  182. Cardozo T, Veazey R (2021) Informed consent disclosure to vaccine trial subjects of risk of COVID-19 vaccines worsening clinical disease. Int J Clin Pract  75(3):13-95.
  183. Zimmermann P, Curtis N (2018) The influence of probiotics on vaccine responses-A systematic review. Vaccine  36(2):207-213.
  184. Zheng Z, Diaz-Arévalo D, Guan H, Zeng M (2018) Noninvasive vaccination against infectious diseases. Hum Vaccin Immunother 14(7):1717-1733.
  185. Criscuolo E, Caputo V, Diotti RA, Sautto GA., Kirchenbaum GA (2019) Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines. Journal of immunology research 2(9):638-648.
  186. Church JA, Parker EP, Kirkpatrick BD, Grassly NC, Prendergast AJ (2019) Interventions to improve oral vaccine performance: a systematic review and meta-analysis. Lancet Infect Dis 19(2):203-214.
  187. Shakoor S, Rao AQ, Shahid N, Yaqoob A, Samiullah TR, et al. (2019) Role of oral vaccines as an edible tool to prevent infectious diseases. Acta Virol 63(3):245-252.

Author Info

Faiza Abdur Rab*
 
Department of Food Science and Technology, University of Karachi, Pakistan
 

Received: 02-Jul-2021 Accepted: 16-Jul-2021 Published: 23-Jul-2021 , DOI: 10.35248/2329-8901.21.9.233

Copyright: This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Top