Determination of Allopurinol and Oxypurinol in Dogs Plasma by High- Performance Liquid Chromatography with an Ultraviolet Detector: Application for Pharmacokinetic Studies

Godoy ALPC^1,2*, De Jesus C¹, De Oliveira ML³, Rocha A³, Pereira MPM³, Larangeira DF^2,4, Lanchote VL³ and Barrouin-Melo SM^2,4*

¹Laboratory of Veterinary Infectology, Hospital-School of Veterinary Medicine, Federal University of Bahia (UFBA), Av. Adhemar de Barros, 500, Salvador, BA, Brazil

²Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, UFBA, Rua Barão de Jeremoabo, 147, Salvador, BA, Brazil

³Department of Clinical, Toxicological and Bromatological Analyzes, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida do Café, S / N, Ribeirão Preto, SP, Brazil

⁴Department of Anatomy, Pathology and Clinics, School of Veterinary Medicine and Animal Science, UFBA, Salvor, BA, Brazil

^*Corresponding Author(s): Godoy ALPC, Laboratory of Toxicology - School of Pharmacy, Federal University of Bahia (UFBA), Rua Barão De Jeremoabo, 147, Salvador, BA, Brazil, Tel: +5571992463177 Email: Barrouin-Melo SM, Laboratory of Veterinary Infectology, Hospital- School of Veterinary Medicine, Federal University of Bahia (UFBA), Av. Adhemar De Barros500, Salvador, BA, 40170- 110, Brazil, Tel: +557132836756 Email: