An LC/MS Assay for Analysis of Vorinostat in Rat Serum and Urine: Application to a Pre-Clinical Pharmacokinetic Study

Elham A. Mohamed^1,2, Mahasen M. Meshali², Casey L. Sayre^1,3, Stephanie E. Martinez^1,3, Connie M. Remsberg¹, Jody K. Takemoto¹, Thanaa M. Borg², Abdel Monem M. Foda² and Neal M. Davies^1,3*

¹College of Pharmacy, Department of Pharmaceutical Sciences, Washington State University, Pullman, WA 99164-6534, USA, E-mail: mohamedea@yahoo.com

²Department of Pharmaceutics, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt, E-mail: mohamedea@yahoo.com

³Faculty of Pharmacy, University of Manitoba, Winnipeg, MB R3T 2N2, Canada, E-mail: mohamedea@yahoo.com

^*Corresponding Author: Dr. Neal M. Davies, Faculty of Pharmacy, University of Manitoba, Winnipeg, MB R3T 2N2, Canada, Tel: 509 335-4754 Email: